Evidence map›Paper›PMID 37547919›Full record

Review3 Biotech2023

Plant-derived nanomaterials (PDNM): a review on pharmacological potentials against pathogenic microbes, antimicrobial resistance (AMR) and some metabolic diseases.

Emmanuel Sunday Okeke, Ekene John Nweze, Emeka Godwin Anaduaka, Charles Obinwanne Okoye, Chioma Assumpta Anosike, Parker Elijah Joshua, Timothy Prince Chidike Ezeorba

Open access · hybridAbstract readReview
In one paragraph

Review in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Emmanuel Sunday OkekeDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, 410001 Enugu Nigeria.
Ekene John NwezeDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, 410001 Enugu Nigeria.
Emeka Godwin AnaduakaDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, 410001 Enugu Nigeria.
Charles Obinwanne OkoyeSchool of Environment and Safety Engineering, Jiangsu University, Zhenjiang, 212013 People's Republic of China.
Chioma Assumpta AnosikeDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, 410001 Enugu Nigeria.
Parker Elijah JoshuaDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, 410001 Enugu Nigeria.
Timothy Prince Chidike EzeorbaDepartment of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, 410001 Enugu Nigeria.ORCID 0000-0002-7077-3282
University of Nigeria · NGJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived nanomaterials (PDNM) have gained significant attention recently due to their potential pharmacological applications against pathogenic microbes, antimicrobial resistance (AMR), and certain metabolic diseases. This review introduces the concept of PDNMs and their unique properties, including their small size, high surface area, and ability to penetrate biological barriers. Besides various methods for synthesizing PDNMs, such as green synthesis techniques that utilize plant extracts and natural compounds, the advantages of using plant-derived materials, such as their biocompatibility, biodegradability, and low toxicity, were elucidated. In addition, it examines the recent and emerging trends in nanomaterials derived from plant approaches to combat antimicrobial resistance and metabolic diseases. The sizes of nanomaterials and their surface areas are vital as they play essential roles in the interactions and relationships between these materials and the biological components or organization. We critically analyze the biomedical applications of nanoparticles which include antibacterial composites for implantable devices and nanosystems to combat antimicrobial resistance, enhance antibiotic delivery, and improve microbial diagnostic/detection systemsIn addition, plant extracts can potentially interfere with metabolic syndrome pathways; hence most nano-formulations can reduce chronic inflammation, insulin resistance, oxidative stress, lipid profile, and antimicrobial resistance. As a result, these innovative plant-based nanosystems may be a promising contender for various pharmacological applications.

Indexed as

Antimicrobial resistance (AMR)Drug deliveryGreen nanoparticlesMetabolic diseasesPlant-derived nanomaterials (PDNMs)

Identifiers

PMID37547919
PMCPMC10403488
OpenAlexW4385580747

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.