Evidence map›Paper›PMID 37548494›Full record

ReviewJournal of feline medicine and surgery2023

Stromal cell therapy in cats with feline chronic gingivostomatitis: current perspectives and future direction.

Iris L Rivas, Maria Soltero-Rivera, Natalia Vapniarsky, Boaz Arzi

Abstract readReview
In one paragraph

Review in Journal of feline medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Mesenchymal Stem Cells in Veterinary Medicine-Still Untapped Potential.Animals : an open access journal from MDPI · 2025
    Review
  4. The prevalence of reasons for tooth extraction in cats.Frontiers in veterinary science · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iris L RivasDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA.ORCID 0000-0003-2971-0674
Maria Soltero-RiveraDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA, USA.ORCID 0000-0003-2272-3966
Natalia VapniarskyDepartment of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA.
Boaz ArziDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA, USA.ORCID 0000-0002-7289-8994

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feline chronic gingivostomatitis (FCGS) is a painful, immune-mediated, oral mucosal inflammatory disease in cats. The etiology of FCGS remains unclear, with evidence pointing potentially toward a viral cause. Full-mouth tooth extraction is the current standard of care, and cats that are non-responsive to extraction therapy may need lifelong medical management and, in some cases, euthanasia. Adipose-derived mesenchymal stromal cells (adMSCs) have been demonstrated to have advantages in the treatment and potentially the cure of non-responsive FCGS in cats. Therefore, adMSCs have attracted a series of ongoing clinical trials in the past decade. AdMSC therapy immediately after full-mouth tooth extraction was not explored, and we postulate that it may benefit the overall success rate of FCGS therapy. Here, we aim to summarize the current knowledge and impact of adMSCs for the therapeutic management of FCGS and to suggest a novel modified approach to further increase the efficacy of FCGS treatment in cats.

Indexed as

Cat DiseasesStomatitisAnimalsCatsStromal CellsGingivostomatitisimmune modulationinflammationstem cell

Identifiers

PMID37548494
PMCPMC10811994

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.