ArticleScientific reports2023
Transcriptome and WGCNA reveal hub genes in sugarcane tiller seedlings in response to drought stress.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 23 citations in OpenAlex.
- Integrated comparative transcriptomics and WGCNA reveal the core transcriptional network and hub genes regulating sucrose accumulation in Saccharum spp.BMC plant biology · 2026Article
- Transcriptome Analysis Coupled with Metabolome Profiling at a Key Time Point Reveals the Molecular Mechanism of Cold Stress Response in Oil Palm (Plants (Basel, Switzerland) · 2026Article
- Identification and functional validation of hub genes responding to waterlogging stress during the filling period in quinoa (Chenopodium Quinoa Willd.).BMC plant biology · 2026Article
- Sugarcane Breeding in the Genomic Era: Integrative Strategies and Emerging Technologies.Plants (Basel, Switzerland) · 2026Review
- Integrated multi-omics analysis reveals hormonal and nutrient networks regulating sugarcane tillering.Frontiers in plant science · 2026Article
- Article
- Co-expression analysis provides a new strategy for mining key metabolites and genes in response to drought stress in Agropyron mongolicum.Plant molecular biology · 2025Article
- Identification of NAC Transcription Factors Associated with Leaf Senescence inInternational journal of molecular sciences · 2025Article
- Morpho-physio-biochemical and gene expression profiling of drought-tolerant sugarcane genotypes (Saccharum hybrids).Molecular biology reports · 2025Article
- Comparative Transcriptomic Analyses Reveal Key Pathways in Response to Cold Stress at the Germination Stage of Quinoa (Plants (Basel, Switzerland) · 2025Article
- Genetic and molecular insights into tiller development and approaches for crop yield improvement.Frontiers in plant science · 2025Review
- Comparative transcriptome and metabolome profiling unveil genotype-specific strategies for drought tolerance in cotton.Frontiers in plant science · 2025Article
- Using WGCNA and transcriptome profiling to identify hub genes for salt stress tolerance in germinating soybean seeds.Frontiers in plant science · 2025Article
- Soil-Mulching Treatment Enhances the Content of Stilbene in Grape Berries: A Transcriptomic and Metabolomic Analysis.Foods (Basel, Switzerland) · 2024Article
- Identification and core gene-mining of Weighted Gene Co-expression Network Analysis-based co-expression modules related to flood resistance in quinoa seedlings.BMC genomics · 2024Article
- Exogenous Melatonin Enhances Cold Tolerance by Regulating the Expression of Photosynthetic Performance, Antioxidant System, and Related Genes in Cotton.Plants (Basel, Switzerland) · 2024Article
- Comprehensive Transcriptome and Proteome Analyses Reveal the Drought Responsive Gene Network in Potato Roots.Plants (Basel, Switzerland) · 2024Article
- Hub Genes and Pathways Related to Lemon (International journal of molecular sciences · 2024Article
- Study of red vine phenotypic plasticity across central-southern Italy sites: an integrated analysis of the transcriptome and weather indices through WGCNA.Frontiers in plant science · 2024Article
- Identification of candidate regulators of the response to early heat stress in climate-adapted wheat landracesFrontiers in plant science · 2023Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drought stress can severely affect sugarcane growth and yield. The objective of this research was to identify candidate genes in sugarcane tillering seedlings in response to drought stress. We performed a comparative phenotypic, physiological and transcriptomic analysis of tiller seedlings of drought-stressed and well-watered "Guire 2" sugarcane, in a time-course experiment (5 days, 9 days and 15 days). Physiological examination reviewed that SOD, proline, soluble sugars, and soluble proteins accumulated in large amounts in tiller seedlings under different intensities of drought stress, while MDA levels remained at a stable level, indicating that the accumulation of osmoregulatory substances and the enhancement of antioxidant enzyme activities helped to limit further damage caused by drought stress. RNA-seq and weighted gene co-expression network analysis (WGCNA) were performed to identify genes and modules associated with sugarcane tillering seedlings in response to drought stress. Drought stress induced huge down-regulated in gene expression profiles, most of down-regulated genes were mainly associated with photosynthesis, sugar metabolism and fatty acid synthesis. We obtained four gene co-expression modules significantly associated with the physiological changes under drought stress (three modules positively correlated, one module negatively correlated), and found that LSG1-2, ERF1-2, SHKA, TIL, HSP18.1, HSP24.1, HSP16.1 and HSFA6A may play essential regulatory roles as hub genes in increasing SOD, Pro, soluble sugar or soluble protein contents. In addition, one module was found mostly involved in tiller stem diameter, among which members of the BHLH148 were important nodes. These results provide new insights into the mechanisms by which sugarcane tillering seedlings respond to drought stress.
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