Evidence map›Paper›PMID 37550741›Full record

ReviewJournal of pharmaceutical policy and practice2023

Acute coronary syndrome and its treatment outcomes in Ethiopia: a systematic review and meta-analysis.

Bekalu Kebede, Melese Getachew, Samuel Agegnew, Ephrem Mebratu Dagnew, Dehnnet Abebe, Anteneh Belayneh, Bantayehu Addis Tegegne, Tiringo Kebede, Mekides Kiflu, Yalemgeta Biyazin and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pharmaceutical policy and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Bekalu KebedePharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Melese GetachewPharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia. meleseget78@gmail.com.ORCID http://orcid.org/0000-0003-3397-0022
Samuel AgegnewPharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Ephrem Mebratu DagnewPharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Dehnnet AbebePharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Anteneh BelaynehPharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Bantayehu Addis TegegnePharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Tiringo KebedeDepartment of Nursing, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Mekides KifluPharmacy Department, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Yalemgeta BiyazinDepartment of Pediatrics and Child Health Nursing, Health Science College, Debre Markos University, Debre Markos, Ethiopia.
Yoseph Merkeb AlamnehDepartment of Biomedical Sciences, School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Debre Markos University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute coronary syndrome (ACS) is the principal cause of death in developing countries including Ethiopia. No study reports the overall patterns of risk factors and burden of in-hospital mortality in Ethiopia. This study, therefore, aimed to assess the magnitude of risk factors, management, and in-hospital mortality of ACS in Ethiopia.

methodsElectronic searching of articles was conducted using PubMed, Science Direct, EMBASE, Scopus, Hinari, and Google Scholar to access articles conducted in Ethiopia. The Preferred Reporting Items for Systematic Reviews checklist was used for identification, eligibility screening, and selection of articles. Data were extracted with an abstraction form prepared with Microsoft Excel and exported to STATA for analysis. Funnel plot, Begg's test, and Egger's test were used to determine publication bias. Heterogeneity between the studies was checked by I

resultsMost (59.367%) of the patients had ST-segment elevation myocardial infarction (STEMI). Hypertension (54.814%) was the leading risk factor for ACS followed by diabetes mellitus (38.549%). Aspirin (56.903%) and clopidogrel (55.266%) were most frequently used in patients with STEMI ACS, respectively. The pooled proportion of in-hospital mortality of ACS was 14.82% which was higher in patients with STEMI (16.116%).

conclusionThe rate of in-hospital mortality is still high which was higher in patients with STEMI. Initiation of treatment must consider the heterogeneity of each patient's risk factor and reperfusion therapy should be implemented in our setting.

Indexed as

Acute coronary syndromeEthiopiaManagementMeta-analysisMortalityRisk factorsSystematic review

Identifiers

PMID37550741
PMCPMC10408155
OpenAlexW4385637372

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.