Evidence map›Paper›PMID 37551586›Full record

ReviewBJPsych open2023

Clinical practice guidelines on the use of deep brain stimulation for the treatment of obsessive-compulsive disorder: systematic review.

Adele Mazzoleni, Shreya Bhatia, Maria A Bantounou, Niraj S Kumar, Monika Dzalto, Roy L Soiza

Open access · goldAbstract readReview
In one paragraph

Review in BJPsych open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Adele MazzoleniBarts and the London School of Medicine and Dentistry, UK.
Shreya BhatiaQueen's University Belfast, Northern Ireland.ORCID https://orcid.org/0000-0001-7913-8341
Maria A BantounouSchool of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK; and National Medical Research Association, London, UK.
Niraj S KumarNational Medical Research Association, London, UK.
Monika DzaltoBrighton and Sussex Medical School, UK.
Roy L SoizaSchool of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.
University of Aberdeen · GBBrighton and Sussex Medical School · GBBritish Medical Association · GBQueen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeep brain stimulation (DBS) has been proposed to improve symptoms of obsessive-compulsive disorder (OCD) but is not yet an established therapy.

aimsTo identify relevant guidelines and assess their recommendations for the use of DBS in OCD.

methodMedline, Embase, American Psychiatric Association PsycInfo and Scopus were searched, as were websites of relevant societies and guideline development organisations. The review was based on the PRISMA recommendations, and the search strategy was verified by a medical librarian. The protocol was developed and registered with PROSPERO (CRD42022353715). The guidelines were assessed for quality using the AGREE II instrument.

resultsNine guidelines were identified. Three guidelines scored >80% on AGREE II. 'Scope and Purpose' and 'Editorial Independence' were the highest scoring domains, but 'Applicability' scores were low. Eight guidelines recommended that DBS is used after all other treatment options have failed to alleviate OCD symptoms. One guideline did not recommend DBS beyond a research setting. Only one guideline performed a cost-effectiveness analysis; the other eight did not provide details on safe or effective DBS protocols.

conclusionDespite a very limited evidence base, eight of the nine identified guidelines supported the use of DBS for OCD as a last line of therapy; however, multiple aspects of DBS provision were not addressed.

Indexed as

AGREE IIclinical practice guidelinesdeep brain stimulationobsessive–compulsive disordersystematic review

Identifiers

PMID37551586
PMCPMC10486236
OpenAlexW4385663293

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.