Evidence map›Paper›PMID 37554272›Full record

ArticleTheranostics2023

Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation.

Wenqiang Xin, Yongli Pan, Wei Wei, Lars Tatenhorst, Irina Graf, Aurel Popa-Wagner, Stefan T Gerner, Sabine Huber, Ertugrul Kilic, Dirk M Hermann and 3 more

Abstract read
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Review
  8. Neuroprotective potential ofVeterinary world · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wenqiang XinDepartment of Neurology, University of Göttingen Medical School, Göttingen, Germany.
Yongli PanDepartment of Neurology, University of Göttingen Medical School, Göttingen, Germany.
Wei WeiDepartment of Neurology, University of Göttingen Medical School, Göttingen, Germany.
Lars TatenhorstDepartment of Neurology, University of Göttingen Medical School, Göttingen, Germany.
Irina GrafDepartment of Neurology, University of Göttingen Medical School, Göttingen, Germany.
Aurel Popa-WagnerDepartment of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Stefan T GernerDepartment of Neurology, University of Giessen Medical School, Giessen, Germany.
Sabine HuberDepartment of Neurology, University of Giessen Medical School, Giessen, Germany.
Ertugrul KilicDepartment of Physiology, Istanbul Medeniyet University, Istanbul, Turkey.
Dirk M HermannDepartment of Neurology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Mathias BährDepartment of Neurology, University of Göttingen Medical School, Göttingen, Germany.
Hagen B HuttnerDepartment of Neurology, University of Giessen Medical School, Giessen, Germany.
Thorsten R DoeppnerDepartment of Neurology, University of Göttingen Medical School, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aquaporin 4Brain InjuriesExtracellular VesiclesStrokeAnimalsGliosisHypoxiaInflammationMiceMicrogliaNeuroinflammatory DiseasesOxygenAqp4 protein, mouseAquaporin 4OxygenAQP4 polarizationastrogliosisCSF flowextracellular vesiclesinflammationmicrogliastroke

Identifiers

PMID37554272
PMCPMC10405850

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.