Evidence map›Paper›PMID 37556305›Full record

ReviewEnvironmental health perspectives2023

Early-Life Exposure to a Mixture of Phenols and Phthalates in Relation to Child Social Behavior: Applying an Evidence-Based Prioritization to a Cohort with Improved Exposure Assessment.

Vicente Mustieles, Matthieu Rolland, Isabelle Pin, Cathrine Thomsen, Amrit K Sakhi, Azemira Sabaredzovic, Gina Muckle, Karine Guichardet, Rémy Slama, Claire Philippat

Open access · diamondAbstract readReview
In one paragraph

Review in Environmental health perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Bisphenol S Exposure and MASLD: A Mechanistic Study in Mice.Environmental health perspectives · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Subacute exposure to DEHP leads to impaired decidual reaction and exacerbates the risk of early miscarriage in mice.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Vicente MustielesUniversity Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, Grenoble, France.ORCID 0000-0002-2010-5438
Matthieu RollandUniversity Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, Grenoble, France.
Isabelle PinPediatric Department, Grenoble Alpes University Hospital, La Tronche, France.
Cathrine ThomsenNorwegian Institute of Public Health, Oslo, Norway.
Amrit K SakhiNorwegian Institute of Public Health, Oslo, Norway.
Azemira SabaredzovicNorwegian Institute of Public Health, Oslo, Norway.
Gina MuckleCentre Hospitalier Universitaire de Québec - Université Laval Research Center, Québec City, Canada.
Karine GuichardetPediatric Department, Grenoble Alpes University Hospital, La Tronche, France.
Rémy SlamaUniversity Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, Grenoble, France.
Claire PhilippatUniversity Grenoble Alpes, Inserm U 1209, CNRS UMR 5309, Team of Environmental Epidemiology Applied to Development and Respiratory Health, Institute for Advanced Biosciences, Grenoble, France.
Centre National de la Recherche Scientifique · FRNorwegian Institute of Public Health · NOUniversité Grenoble Alpes · FRCentre hospitalier universitaire de Québec · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies aiming at relating exposure to phenols and phthalates with child social behavior characterized exposure using one or a few spot urine samples, resulting in substantial exposure misclassification. Moreover, early infancy exposure was rarely studied.

objectivesWe aimed to examine the associations of phthalates and phenols with child social behavior in a cohort with improved exposure assessment and to

methodsAmong 406 mother-child pairs from the French Assessment of Air Pollution exposure during Pregnancy and Effect on Health (SEPAGES) cohort, 25 phenols/phthalate metabolites were measured in within-subject pools of repeated urine samples collected at the second and third pregnancy trimesters (

resultsPrioritized compounds included bisphenol A, bisphenol S, triclosan (TCS), diethyl-hexyl phthalate ( DISCUSSION: The literature search allowed us to adapt our statistical analysis according to the weight of evidence and create a corpus of experimental and epidemiological knowledge to better interpret our findings. Early infancy appears to be a sensitive exposure window that should be further investigated. https://doi.org/10.1289/EHP11798.

Indexed as

Diethylhexyl PhthalateEnvironmental PollutantsPhthalic AcidsTriclosanBayes TheoremDibutyl PhthalateEnvironmental ExposureFemaleHumansInfantInfant, NewbornMothersPhenolsPregnancyDibutyl PhthalateDiethylhexyl PhthalateEnvironmental PollutantsPhenolsphthalic acidPhthalic AcidsTriclosan

Identifiers

PMID37556305
PMCPMC10411634
OpenAlexW4385715373

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.