ArticleBMC cardiovascular disorders2023
Outcomes of pregnancy in women with different types of pulmonary hypertension.
Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Anesthesia during cesarean section in women with congenital heart disease : Experience from a certified university hospital for adults with congenital heart disease in Germany-Retrospective analysis from 2013-2023.Die Anaesthesiologie · 2026Article
- Maternal and fetal outcomes in patients with congenital heart disease associated with pulmonary arterial hypertension in high-altitude areas: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Successful Vaginal Birth in Severe Idiopathic Pulmonary Arterial Hypertension: Lessons Learned From a Cardio-Obstetric Challenge.JACC. Case reports · 2025Article
- Maternal and neonatal outcomes in pregnancies complicated with pulmonary hypertension: a retrospective cohort study.European journal of medical research · 2025Article
- Pregnancy in patients with pulmonary hypertension: a systematic review and meta-analysis with meta-regression.Journal of thoracic disease · 2025Article
- Analysis of Clinical Characteristics of 54 Dead Pregnant Patients With Pulmonary Hypertension.Pulmonary circulation · 2025Article
- Navigating pregnancy with cardiovascular disease: pathophysiology, risk stratification, and maternal-fetal outcomes.Turkish journal of medical sciences · 2025Review
- Management of pulmonary hypertension in special conditions.The European respiratory journal · 2024Review
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPulmonary hypertension (PH) is considered to increase maternal and fetal risk, and we attempt to explore pregnancy outcomes in women with different types of PH.
methodsWe retrospectively analyzed the clinical data of pregnant women with PH who were admitted to Anzhen Hospital from January 2010 to December 2019, and followed up on these parturients and their offspring.
resultsThree hundred and sixty-six pregnant women with PH were collected, including 265 pulmonary arterial hypertension (PAH) associated with congenital heart disease (CHD), 65 PH caused by left heart disease, 12 idiopathic PH, and 24 PH associated with other diseases. Maternal mean age was 28.4 ± 4.4 years and 72.1% were nulliparous. The estimated systolic pulmonary artery pressure was < 50 mmHg in 40.2% of patients, 50-70 mmHg in 23.2%, and > 70 mmHg in 36.6%. In more than 94% of women, a diagnosis of PH was made before pregnancy. During pregnancy, heart failure occurred in 15% of patients. Cesarean section was performed in 90.5% (20.4% emergency). Complications included fetal mortality (0.5%), preterm delivery (40.4%), and low birth weight (37.7%). A total of 20 mothers died (5.5%). The highest mortality rate was found in patients with idiopathic PH (4/12, 33.3%). A total of 12 children died (3.3%), 5 (1.4%) of them after discharge from the hospital, and 7 (1.9%) were in hospital.
conclusionsAlthough most of these women are fertile, PH does increase maternal and fetal risk. Women with idiopathic PH and Eisenmenger syndrome are not recommended to have children.
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