Evidence mapPaperPMID 37563160Full record

ArticleNature communications2023

Structural basis of agonist specificity of α

Minfei Su, Jinan Wang, Guoqing Xiang, Hung Nguyen Do, Joshua Levitz, Yinglong Miao, Xin-Yun Huang

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Discovery of a peripherally restricted αCell reports. Medicine · 2026
    Article
  2. Article
  3. Article
  4. αPharmaceuticals (Basel, Switzerland) · 2025
    Review
  5. GPCR drug discovery: new agents, targets and indications.Nature reviews. Drug discovery · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Signalling of Adrenoceptors: Canonical Pathways and New Paradigms.Handbook of experimental pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Minfei Su *Department of Physiology and Biophysics, Weill Cornell Medical College of Cornell University, New York, NY, 10065, USA.
Jinan Wang *Center for Computational Biology and Department of Molecular Biosciences, University of Kansas, Lawrence, KS, 66047, USA.
Guoqing XiangDepartment of Biochemistry, Weill Cornell Medical College of Cornell University, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0003-1111-9675
Hung Nguyen DoCenter for Computational Biology and Department of Molecular Biosciences, University of Kansas, Lawrence, KS, 66047, USA.ORCID http://orcid.org/0000-0002-6497-4096
Joshua LevitzDepartment of Biochemistry, Weill Cornell Medical College of Cornell University, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0002-8169-6323
Yinglong MiaoCenter for Computational Biology and Department of Molecular Biosciences, University of Kansas, Lawrence, KS, 66047, USA. miao@ku.edu.ORCID http://orcid.org/0000-0003-3714-1395
Xin-Yun HuangDepartment of Physiology and Biophysics, Weill Cornell Medical College of Cornell University, New York, NY, 10065, USA. xyhuang@med.cornell.edu.ORCID http://orcid.org/0000-0003-2534-2587
Cornell University · USUniversity of Kansas · US

Funding

NIGMS NIH HHS P41 GM103310NIGMS NIH HHS R01 GM132572NIGMS NIH HHS R01 GM138676NIH HHS S10 OD019994
6 · The paper itself

Abstract

α

Indexed as

EpinephrineReceptors, Adrenergic, alpha-1Signal TransductionEpinephrineReceptors, Adrenergic, alpha-1

Identifiers

PMID37563160
PMCPMC10415349
OpenAlexW4385723578

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.