ArticleCardiovascular diabetology2023
Nonlinear relationship between atherogenic index of plasma and the risk of prediabetes: a retrospective study based on Chinese adults.
Article in Cardiovascular diabetology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed.
- Non-traditional lipid-inflammatory parameters estimate the risk of stroke in middle-aged and older Chinese adults: a nationwide prospective cohort study.Journal of advanced research · 2026Article
- Association of Glycemic Status with Disability, Relapse Activity, Inflammatory Markers, and Metabolic Profile in Patients with Multiple Sclerosis.Journal of clinical medicine · 2026Article
- Physical Activity Modifies the Association Between Atherogenic Index of Plasma and New-Onset Diabetes in Middle-Aged and Older Adults.Healthcare (Basel, Switzerland) · 2026Article
- Nonlinear association of triglyceride-glucose body mass index with all-cause mortality in postmenopausal women, a retrospective cohort study: Evidence from the 2001 to 2014 National Health and nutrition examination survey.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- The association between atherogenic index of plasma (AIP) and ultrasound attenuation parameter (UAP) in Chinese adults: a cross-sectional study.Scientific reports · 2026Article
- Association of Atherogenic Index of Plasma With Prediabetics-A Cross-Sectional Study.Endocrinology, diabetes & metabolism · 2026Review
- Impact of control patterns for the atherogenic index of plasma and its obesity-associated indices on transitions in prediabetes glycemic status: results from the CHARLS national cohort study.Lipids in health and disease · 2026Article
- Article
- Association of Nontraditional Lipid Parameters With Long-Term Prognosis of Acute Ischemic Stroke: A Principal Components Analysis.Journal of the American Heart Association · 2026Article
- Association between atherogenic index of plasma in early pregnancy and risk of preeclampsia: a multicenter cohort study.Frontiers in nutrition · 2026Article
- Article
- The atherogenic index of plasma is associated with subclinical cardiac systolic dysfunction among obese patients: a cross-sectional study.Frontiers in nutrition · 2026Article
- BMI-specific nonlinear associations and threshold effects of the atherogenic index of plasma on incident prediabetes: insights from 100473 Chinese adults.Frontiers in endocrinology · 2026Article
- Linear associations of triglyceride-glucose body mass index and atherogenic index of plasma with the risk of diabetes: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Prognostic value of the AIP index in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.Frontiers in nutrition · 2026Article
- Blood pressure-stratified associations of the atherogenic index of plasma with all-cause mortality: a 10-year rural cohort study in China.Frontiers in cardiovascular medicine · 2026Article
- Inflammatory markers mediate association of AIP with kidney failure risk: data from National Health and Nutrition Examination Survey (NHANES) 2005-2018.Renal failure · 2025Article
- Association of triglyceride-glucose index and atherogenic index of plasma with sarcopenia across different glucose metabolism states: the mediating role of oxidative stress and chronic inflammation.European journal of medical research · 2025Article
- Joint analysis of atherogenic index of plasma clusters and a body shape index trajectories in incident stroke risk.Lipids in health and disease · 2025Article
- Association between atherogenic index of plasma and sepsis in critically ill patients with ischemic stroke: a retrospective cohort study using propensity score and machine learning approaches.Lipids in health and disease · 2025Article
2 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
backgroundThe atherogenic index of plasma (AIP) can reflect the burden of atherosclerosis. Hyperglycemia is one of the leading causes of atherosclerosis. However, the relationship between AIP and prediabetes is rarely studied. Therefore, we aimed to explore the relationship between AIP and prediabetes.
methodsThis retrospective cohort study recruited 100,069 Chinese adults at the Rich Healthcare Group from 2010 to 2016. AIP was calculated according to Log10 (triglyceride/high-density lipoprotein cholesterol) formula. Cox regression method, sensitivity analyses and subgroup analyses were used to examine the relationship between AIP and prediabetes. Cox proportional hazards regression with cubic spline functions and smooth curve fitting was performed to explore the non-linearity between AIP and prediabetes. The two-piece Cox proportional hazards regression model was used to determine the inflection point of AIP on the risk of prediabetes.
resultsAfter adjusting for confounding covariates, AIP was positively associated with prediabetes (HR: 1.41, 95%CI: 1.31-1.52, P < 0.0001). The two-piecewise Cox proportional hazards regression model discovered that the AIP's inflection point was 0.03 (P for log-likelihood ratio test < 0.001). AIP was positively associated with the risk of prediabetes when AIP ≤ 0.03 (HR: 1.90, 95%CI: 1.66-2.16, P < 0.0001). In contrast, When AIP > 0.03, their association was not significant (HR: 1.04, 95%CI: 0.91-1.19, P = 0.5528).
conclusionThis study shows that AIP was positively and non-linearly associated with the risk of prediabetes after adjusting for other confounding factors. When AIP ≤ 0.03, AIP was positively associated with the risk of prediabetes.
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