Evidence map›Paper›PMID 37568498›Full record

ArticleJournal of clinical medicine2023

Sex-Based Differences in Clinical Characteristics and Outcomes among Patients with Peripheral Artery Disease: A Retrospective Analysis.

Giuseppe De Matteis, Federico Biscetti, Davide Antonio Della Polla, Amato Serra, Maria Livia Burzo, Mariella Fuorlo, Maria Anna Nicolazzi, Angela Novelli, Angelo Santoliquido, Giovanni Gambassi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Implications of inflammation and sex in lower extremity arterial disease.European journal of clinical investigation · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Giuseppe De MatteisDepartment of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.ORCID 0000-0003-2982-3951
Federico BiscettiCardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.ORCID 0000-0001-7449-657X
Davide Antonio Della PollaEmergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Amato SerraDepartment of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Maria Livia BurzoDepartment of Internal Medicine, Ospedale Santo Spirito in Sassia, 00193 Rome, Italy.
Mariella FuorloEmergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Maria Anna NicolazziCardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Angela NovelliEmergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Angelo SantoliquidoFaculty of Medicine and Surgery, Rome Campus, Università Cattolica del Sacro Cuore, 20123 Rome, Italy.
Giovanni GambassiDepartment of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Antonio GasbarriniDepartment of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Andrea FlexCardiovascular Internal Medicine, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Francesco FranceschiEmergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.
Marcello CovinoEmergency Department, Fondazione Policlinico Universitario A. Gemelli, IRCCS, 00168 Rome, Italy.ORCID 0000-0002-6709-2531
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · ITOspedale di Santo Spirito · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral arterial disease (PAD) is a prevalent medical condition associated with high mortality and morbidity rates. Despite the high clinical burden, sex-based differences among PAD patients are not well defined yet, in contrast to other atherosclerotic diseases. This study aimed to describe sex-based differences in clinical characteristics and outcomes among hospitalized patients affected by PAD. This was a retrospective study evaluating all patients with a diagnosis of PAD admitted to the Emergency Department from 1 December 2013 to 31 December 2021. The primary endpoint of the study was the difference between male and female PAD patients in cumulative occurrence of Major Adverse Cardiovascular Events (MACEs) and Major Adverse Limb Events. A total of 1640 patients were enrolled. Among them, 1103 (67.3%) were males while females were significantly older (median age of 75 years vs. 71 years;

Indexed as

limb amputationsMACEMALEperipheral artery diseaserevascularizationsex

Identifiers

PMID37568498
PMCPMC10420161
OpenAlexW4385542265

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.