Evidence map›Paper›PMID 37569273›Full record

ArticleInternational journal of molecular sciences2023

Effective and Selective Ru(II)-Arene Complexes Containing 4,4'-Substituted 2,2' Bipyridine Ligands Targeting Human Urinary Bladder Cancer Cells.

Mathiyan Muralisankar, Jun-Ru Chen, Jebiti Haribabu, Shyue-Chu Ke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. RutheniumMolecules (Basel, Switzerland) · 2024
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mathiyan MuralisankarPhysics Department, National Dong Hwa University, Hualien 97401, Taiwan.ORCID 0000-0002-6413-6631
Jun-Ru ChenPhysics Department, National Dong Hwa University, Hualien 97401, Taiwan.
Jebiti HaribabuFacultad de Medicina, Universidad de Atacama, Copayapu 485, Copiapo 1531772, Chile.ORCID 0000-0001-8855-032X
Shyue-Chu KePhysics Department, National Dong Hwa University, Hualien 97401, Taiwan.
National Dong Hwa University · TWUniversity of Atacama · CL

Funding

National Science and Technology council, Taiwan MOST111-2123-M-259-002
6 · The paper itself

Abstract

Cisplatin-based chemotherapy is a common regimen for bladder cancer, a life-threatening cancer with more than 500,000 new cases worldwide annually. Like many other metallodrugs, cisplatin causes severe side effects for its general toxicity. Organoruthenium is known for its structural stability, good anticancer activity, and possible low general toxicity. Here, we have prepared and characterized a series of water-soluble ruthenium-arene complexes with N,N'-chelating ligands: [Ru(II)-η

Indexed as

Antineoplastic AgentsCoordination ComplexesRutheniumUrinary Bladder Neoplasms2,2'-DipyridylAnimalsCell Line, TumorChlorocebus aethiopsCisplatinEndothelial CellsHumansLigandsMolecular Docking SimulationVero Cells2,2'-DipyridylAntineoplastic AgentsCisplatinCoordination ComplexesLigandsRutheniumanticancer agentbladder cancerorganorutheniumruthenium-arene complex

Identifiers

PMID37569273
PMCPMC10418970
OpenAlexW4385274091

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.