Evidence map›Paper›PMID 37569480›Full record

ArticleInternational journal of molecular sciences2023

Oral Spirochete

Chairmandurai Aravindraja, Syam Jeepipalli, Krishna Mukesh Vekariya, Ruben Botello-Escalante, Edward K L Chan, Lakshmyya Kesavalu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Metagenomic Comparison of Gut Microbes ofAnimals : an open access journal from MDPI · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. International journal of molecular sciences · 2024
    Article
  13. Unique miRomics Expression Profiles inInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chairmandurai AravindrajaDepartment of Periodontology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Syam JeepipalliDepartment of Periodontology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-2769-8619
Krishna Mukesh VekariyaDepartment of Periodontology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-3106-400X
Ruben Botello-EscalanteDepartment of Periodontology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-0107-846X
Edward K L ChanDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.
Lakshmyya KesavaluDepartment of Periodontology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-8828-8656
University of Florida · US

Funding

Dominant microRNAs as biomarkers in innate immunity and periodontitisR01DE028536 · NIDCR · UNIVERSITY OF FLORIDA · PI LAKSHMYYA, KESAVALU NAIDU · 2020 to 2024
$1.9M
NIDCR NIH HHS R01 DE028536
6 · The paper itself

Abstract

miRNAs are major regulators of eukaryotic gene expression and host immunity, and play an important role in the inflammation-mediated pathways in periodontal disease (PD) pathogenesis. Expanding our previous observation with the global miRNA profiling using partial human mouth microbes, and lack of in vivo studies involving oral spirochete

Indexed as

Communicable DiseasesMicroRNAsPeriodontal DiseasesPeriodontitisAnimalsBiomarkersFemaleGene Expression ProfilingHumansKineticsMaleMiceSpirochaetalesTreponemaTreponema denticolaBiomarkersMicroRNAsMIRN126 microRNA, humanMIRN378 microRNA, mouseMIRN486 microRNA, humanmiRNAsNanoString analysisperiodontal diseaseT. denticolatransient miRNA expression

Identifiers

PMID37569480
PMCPMC10418472
OpenAlexW4385349647

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.