Evidence map›Paper›PMID 37569482›Full record

ArticleInternational journal of molecular sciences2023

Differential Responses of Retinal Neurons and Glia Revealed via Proteomic Analysis on Primary and Secondary Retinal Ganglion Cell Degeneration.

Jacky M K Kwong, Joseph Caprioli, Joanne C Y Lee, Yifan Song, Feng-Juan Yu, Jingfang Bian, Ying-Hon Sze, King-Kit Li, Chi-Wai Do, Chi-Ho To and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Jacky M K KwongOphthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-6968-1754
Joseph CaprioliOphthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, CA 90095, USA.
Joanne C Y LeeOphthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, CA 90095, USA.
Yifan SongOphthalmology, Stein Eye Institute, University of California Los Angeles, Los Angeles, CA 90095, USA.
Feng-Juan YuCentre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0001-8719-2217
Jingfang BianCentre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0003-0464-1705
Ying-Hon SzeCentre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0002-2724-8968
King-Kit LiCentre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.
Chi-Wai DoCentre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0002-7720-7507
Chi-Ho ToCentre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0002-1938-8397
Thomas Chuen LamCentre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0002-3511-5620
Hong Kong Polytechnic University · HKUniversity of California, Los Angeles · US

Funding

InnoHK initiative and the Hong Kong Special Administrative Region Government CEVRResearch Centre for SHARP Vision P0039545, P0039595Research to Prevent Blindness UnrestrictedShenzhen Science and Technology Innovation Commission JCYJ20180507183409601
6 · The paper itself

Abstract

To explore the temporal profile of retinal proteomes specific to primary and secondary retinal ganglion cell (RGC) loss. Unilateral partial optic nerve transection (pONT) was performed on the temporal side of the rat optic nerve. Temporal and nasal retinal samples were collected at 1, 4 and 8 weeks after pONT (n = 4 each) for non-biased profiling with a high-resolution hybrid quadrupole time-of-flight mass spectrometry running on label-free SWATH

Indexed as

NeurogliaProteomeProteomicsRetinal DegenerationRetinal Ganglion CellsRetinal NeuronsAnimalsMaleOptic Nerve InjuriesRatsRats, Sprague-DawleyProteomeganglion cellglaucomamass spectrometryneurodegenerationoptic nerveproteomics

Identifiers

PMID37569482
PMCPMC10418669
OpenAlexW4385342513

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.