Evidence map›Paper›PMID 37569538›Full record

ArticleInternational journal of molecular sciences2023

Whole Transcriptome Analysis of Substantia Nigra in Mice with MPTP-Induced Parkinsonism Bearing Defective Glucocerebrosidase Activity.

Tatiana Usenko, Anastasia Bezrukova, Margarita M Rudenok, Katerina Basharova, Maria I Shadrina, Petr A Slominsky, Ekaterina Zakharova, Sofya Pchelina

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Tatiana UsenkoPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», 188300 Gatchina, Russia.ORCID 0000-0002-5132-2283
Anastasia BezrukovaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», 188300 Gatchina, Russia.
Margarita M RudenokInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Katerina BasharovaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», 188300 Gatchina, Russia.
Maria I ShadrinaInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Petr A SlominskyInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Ekaterina ZakharovaResearch Center for Medical Genetics, Laboratory of Hereditary Metabolic Diseases, 115522 Moscow, Russia.
Sofya PchelinaPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre «Kurchatov Institute», 188300 Gatchina, Russia.
First Pavlov State Medical University of St. Petersburg · RUInstitute of Molecular Genetics · RUKurchatov Institute · RUResearch Centre for Medical Genetics · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 121060200125-2Russian Science Foundation 19-15-00315
6 · The paper itself

Abstract

Mutations in the

Indexed as

MPTP PoisoningParkinson DiseaseParkinsonian Disorders1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineAnimalsDisease Models, AnimalGene Expression ProfilingGlucosylceramidaseMiceMice, Inbred C57BLPhosphatidylinositol 3-KinasesSubstantia Nigra1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineGba protein, mouseGlucosylceramidasePhosphatidylinositol 3-Kinases1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)conduritol-β-epoxide (CBE)Parkinson’s diseasesubstantia nigra (SN)transcriptome

Identifiers

PMID37569538
PMCPMC10418497
OpenAlexW4385399720

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.