Evidence map›Paper›PMID 37569615›Full record

ArticleInternational journal of molecular sciences2023

Radotinib Decreases Prion Propagation and Prolongs Survival Times in Models of Prion Disease.

Yeong-Gon Choi, Byungki Jang, Jeong-Ho Park, Min-Woo Choi, Gong Yeal Lee, Dae Jin Cho, Hong Youp Kim, Hae Kyoung Lim, Won Jae Lee, Eun-Kyoung Choi and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. CpG oligodeoxynucleotide reduces PrPMolecules and cells · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yeong-Gon ChoiIlsong Institute of Life Science, Hallym University, Youngdeungpo-gu, Seoul 07247, Republic of Korea.
Byungki JangIlsong Institute of Life Science, Hallym University, Youngdeungpo-gu, Seoul 07247, Republic of Korea.
Jeong-Ho ParkIlsong Institute of Life Science, Hallym University, Youngdeungpo-gu, Seoul 07247, Republic of Korea.
Min-Woo ChoiIlsong Institute of Life Science, Hallym University, Youngdeungpo-gu, Seoul 07247, Republic of Korea.
Gong Yeal LeeIl Yang Pharm Co., Ltd., 37, Hagal-ro, 136beon-gil, Giheung-gu, Yongin-si 17096, Republic of Korea.
Dae Jin ChoIl Yang Pharm Co., Ltd., 37, Hagal-ro, 136beon-gil, Giheung-gu, Yongin-si 17096, Republic of Korea.
Hong Youp KimIl Yang Pharm Co., Ltd., 37, Hagal-ro, 136beon-gil, Giheung-gu, Yongin-si 17096, Republic of Korea.
Hae Kyoung LimIl Yang Pharm Co., Ltd., 37, Hagal-ro, 136beon-gil, Giheung-gu, Yongin-si 17096, Republic of Korea.
Won Jae LeeIl Yang Pharm Co., Ltd., 37, Hagal-ro, 136beon-gil, Giheung-gu, Yongin-si 17096, Republic of Korea.
Eun-Kyoung ChoiIlsong Institute of Life Science, Hallym University, Youngdeungpo-gu, Seoul 07247, Republic of Korea.ORCID 0000-0002-9251-8442
Yong-Sun KimIlsong Institute of Life Science, Hallym University, Youngdeungpo-gu, Seoul 07247, Republic of Korea.
Hallym University · KRIl-Yang Pharmaceutical (South Korea) · KR

Funding

Ministry of Health and Welfare HI16C0965
6 · The paper itself

Abstract

The conversion of cellular prion protein (PrP

Indexed as

Prion DiseasesPrionsScrapieAnimalsBenzamidesBrainCricetinaePrPSc ProteinsPyrazinesSheep4-methyl-N-(3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl)-3-(4-pyrazin-2-ylpyrimidin-2-ylamino)benzamideBenzamidesPrionsPrPSc ProteinsPyrazinesdrug repositioningneurodegenerationprionradotinib

Identifiers

PMID37569615
PMCPMC10419185
OpenAlexW4385429328

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.