Evidence map›Paper›PMID 37569725›Full record

ArticleInternational journal of molecular sciences2023

Vitamin D Receptor Deficiency Upregulates Pulmonary Artery Kv7 Channel Activity.

Miguel A Olivencia, Marta Villegas-Esguevillas, Maria Sancho, Bianca Barreira, Elena Paternoster, Rui Adão, María Jesús Larriba, Angel Cogolludo, Francisco Perez-Vizcaino

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Miguel A OlivenciaDepartment of Pharmacology and Toxicology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-9563-8191
Marta Villegas-EsguevillasDepartment of Pharmacology and Toxicology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.
Maria SanchoCiber Enfermedades Respiratorias (CIBERES), 28029 Madrid, Spain.
Bianca BarreiraDepartment of Pharmacology and Toxicology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-0338-8456
Elena PaternosterDepartment of Pharmacology and Toxicology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.
Rui AdãoDepartment of Pharmacology and Toxicology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-2203-436X
María Jesús LarribaInstituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, 28029 Madrid, Spain.ORCID 0000-0001-9035-7414
Angel CogolludoDepartment of Pharmacology and Toxicology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1382-1698
Francisco Perez-VizcainoDepartment of Pharmacology and Toxicology, School of Medicine, University Complutense of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-6309-7418
Universidad Complutense de Madrid · ESConsejo Superior de Investigaciones Científicas · ES

Funding

Ministerio de Ciencia e Innovación PID2020-117939RB-I00 PID2019-104867RB-I00
6 · The paper itself

Abstract

Recent evidence suggests that vitamin D is involved in the development of pulmonary arterial hypertension (PAH). The aim of this study was to analyze the electrophysiological and contractile properties of pulmonary arteries (PAs) in vitamin D receptor knockout mice (

Indexed as

Potassium Channels, Voltage-GatedPulmonary ArteryAnimalsHumansKCNQ Potassium ChannelsMiceMice, KnockoutMuscle, Smooth, VascularRatsReceptors, CalcitriolVitamin DKCNE4 protein, mouseKCNQ Potassium ChannelsPotassium Channels, Voltage-GatedReceptors, CalcitriolVDR protein, humanVitamin DKCNEKv7 channelspulmonary hypertensionvitamin D receptor

Identifiers

PMID37569725
PMCPMC10418734
OpenAlexW4385497783

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.