Evidence map›Paper›PMID 37569893›Full record

ArticleInternational journal of molecular sciences2023

E-Selectin, ICAM-1, and ET-1 Biomarkers Address the Concern of the Challenging Diagnosis of Interstitial Lung Disease in Patients with Autoimmune Diseases.

Verónica Pulito-Cueto, Sara Remuzgo-Martínez, Fernanda Genre, Belén Atienza-Mateo, Víctor M Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, María Sebastián Mora-Gil, Virginia Portilla, Alfonso Corrales and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. E-selectin in vascular pathophysiology.Frontiers in immunology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Verónica Pulito-CuetoImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.ORCID 0000-0002-3534-8467
Sara Remuzgo-MartínezMarqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.ORCID 0000-0003-4455-7241
Fernanda GenreMarqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.
Belén Atienza-MateoImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.ORCID 0000-0001-7119-0786
Víctor M Mora-CuestaImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.ORCID 0000-0002-8161-0462
David Iturbe-FernándezImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.
Leticia Lera-GómezDepartment of Microbiology, Hospital Universitario Marqués de Valdecilla, 39008 Santander, Spain.
María Sebastián Mora-GilImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.
Virginia PortillaImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.
Alfonso CorralesImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.
Ricardo BlancoImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.
José M CifriánImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.
Miguel A González-GayMarqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.ORCID 0000-0002-7924-7406
Raquel López-MejíasImmunopathology Group, Marqués de Valdecilla University Hospital-Marqués de Valdecilla Research Institute (IDIVAL), 39011 Santander, Spain.ORCID 0000-0003-0548-2689
Marqués de Valdecilla University Hospital · ESInstituto de Investigación Marqués de Valdecilla · ESUniversidad de Cantabria · ES

Funding

ISCIII-ESF CPII21/00004ISCIII-ESF PI21/00042
6 · The paper itself

Abstract

Interstitial lung disease (ILD) constitutes the most critical comorbidity in autoimmune diseases (ADs) and its early diagnosis remains a challenge for clinicians. Accordingly, we evaluated whether E-selectin, ICAM-1, and ET-1, key molecules in endothelial damage, could be useful biomarkers for the detection of AD-ILD

Indexed as

Arthritis, RheumatoidAutoimmune DiseasesIdiopathic Pulmonary FibrosisLung Diseases, InterstitialScleroderma, SystemicBiomarkersE-SelectinHumansIntercellular Adhesion Molecule-1LungBiomarkersE-SelectinIntercellular Adhesion Molecule-1autoimmune diseasesbiomarkersE-selectinET-1ICAM-1interstitial lung diseasepulmonary fibrosisrheumatoid arthritissystemic sclerosis

Identifiers

PMID37569893
PMCPMC10420063
OpenAlexW4385630533

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.