Evidence map›Paper›PMID 37571403›Full record

Trial reportNutrients2023

Intake of

Gunilla Önning, Caroline Montelius, Magnus Hillman, Niklas Larsson

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gunilla ÖnningBiomedical Nutrition, Pure and Applied Biochemistry, Lund University, 222 00 Lund, Sweden.
Caroline MonteliusProbi AB, 223 70 Lund, Sweden.
Magnus HillmanDiabetes Research Laboratory, Department of Clinical Sciences Lund, Lund University, 221 84 Lund, Sweden.ORCID 0000-0001-6749-2829
Niklas LarssonProbi AB, 223 70 Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe usage of probiotics has expanded beyond the areas of gut and immune health improvement. Several studies have shown the positive impact associated between probiotics and stress, cognition, and mood; a relationship referred to as the gut-brain axis.

methodThe aim of this exploratory study was to evaluate the effect of the probiotic strain

resultsPerceived stress and awakening cortisol were significantly reduced over time in both groups. A significant improvement in four cognition tests after consumption of LPHEAL9 compared to placebo was observed (rapid information processing test, numeric working memory test, paired associated learning, and word recall,

conclusionsIntake of LPHEAL9 significantly improved cognitive functions compared to the placebo, potentially by ameliorating aspects of mood and sleep.

Indexed as

Lactiplantibacillus plantarumProbioticsAffectCognitionDouble-Blind MethodHumansLearningcognitiongut–brain axisinflammationL. plantarummoodprobioticssleepstresstryptophanworking memory

Identifiers

PMID37571403
PMCPMC10421450

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.