Evidence map›Paper›PMID 37575476›Full record

ArticleFunction (Oxford, England)2023

Computational Modeling of Substrate-Dependent Mitochondrial Respiration and Bioenergetics in the Heart and Kidney Cortex and Outer Medulla.

Shima Sadri, Xiao Zhang, Said H Audi, Allen W Cowley, Ranjan K Dash

Open access · goldAbstract read
In one paragraph

Article in Function (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Mechanistic Modeling of MCUx Gatekeeping, CaAmerican journal of physiology. Cell physiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Sex dimorphism and substrate dependency of liver mitochondrial bioenergetics and HAmerican journal of physiology. Gastrointestinal and liver physiology · 2025
    Article
  7. Article
  8. Complex II ambiguities-FADHThe Journal of biological chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shima SadriDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Xiao ZhangDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Said H AudiDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Allen W CowleyDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0002-0801-6248
Ranjan K DashDepartment of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0001-6751-0679
Medical College of Wisconsin · USMarquette University · US

Funding

High Salt Remodels Renal Cortical and Proximal Tubular Metabolism: Metabolic Fuels, Oxidative Stress, and HypertensionR01HL151587 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Allen W Cowley, Ranjan K Dash · 2021 to 2026
$3.7M
NHLBI NIH HHS R01 HL151587
6 · The paper itself

Abstract

Integrated computational modeling provides a mechanistic and quantitative framework to characterize alterations in mitochondrial respiration and bioenergetics in response to different metabolic substrates

Indexed as

NADOxygen ConsumptionAnimalsComputer SimulationEnergy MetabolismKidneyKidney CortexMitochondriaRatsRespirationNADcomputational modelingforward and reverse electron transfermitochondrial metabolismoxidative phosphorylationrespiration and bioenergeticssubstrate utilization

Identifiers

PMID37575476
PMCPMC10413947
OpenAlexW4385274289

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.