Evidence map›Paper›PMID 37575482›Full record

ArticleFunction (Oxford, England)2023

Metabolic Responses of Normal Rat Kidneys to a High Salt Intake.

Satoshi Shimada, Brian R Hoffmann, Chun Yang, Theresa Kurth, Andrew S Greene, Mingyu Liang, Ranjan K Dash, Allen W Cowley

Open access · goldAbstract read
In one paragraph

Article in Function (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Retinal vascular dysfunction in the MthfrAlzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Article
  7. Article
  8. Renal Medulla in Hypertension.Hypertension (Dallas, Tex. : 1979) · 2024
    Review
  9. Deletion ofiScience · 2024
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Satoshi ShimadaDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0001-5293-572X
Brian R HoffmannMass Spectrometry and Protein Chemistry, Protein Sciences, The Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0002-7526-6335
Chun YangDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0003-3307-1609
Theresa KurthDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Andrew S GreeneMass Spectrometry and Protein Chemistry, Protein Sciences, The Jackson Laboratory, Bar Harbor, ME 04609, USA.ORCID 0000-0002-3191-2112
Mingyu LiangDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0002-6970-989X
Ranjan K DashDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0001-6751-0679
Allen W CowleyDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0002-0801-6248
Medical College of Wisconsin · USJackson Laboratory · USMarquette University · US

Funding

Therapeutic Effects of mTOR Inhibition in Salt-Sensitive HypertensionP01HL116264 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI MATTSON, DAVID L. · 2013 to 2021
$18.7M
Sequencing Coordination and Data Analysis CoreP01HL149620 · NHLBI · UNIVERSITY OF ARIZONA · PI LIANG, MINGYU · 2020 to 2024
$11.8M
High Salt Remodels Renal Cortical and Proximal Tubular Metabolism: Metabolic Fuels, Oxidative Stress, and HypertensionR01HL151587 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Allen W Cowley, Ranjan K Dash · 2021 to 2026
$3.7M
Thermo Scientific Orbitrap Fusion Lumos Tribrid Mass Spectrometer SystemS10OD026816 · OD · JACKSON LABORATORY · PI AHLF WHEATCRAFT, DOROTHY R · 2020 to 2020
$997k
American Heart Association-American Stroke Association 23POST1008714NHLBI NIH HHS P01 HL116264NHLBI NIH HHS P01 HL149620NHLBI NIH HHS R01 HL151587NIH HHS S10 OD026816
6 · The paper itself

Abstract

In this study, novel methods were developed, which allowed continuous (24/7) measurement of arterial blood pressure and renal blood flow in freely moving rats and the intermittent collection of arterial and renal venous blood to estimate kidney metabolic fluxes of O

Indexed as

Sodium ChlorideSodium Chloride, DietaryAnimalsBlood PressureKidneyRatsRats, Sprague-DawleyRNA, MessengerRNA, MessengerSodium ChlorideSodium Chloride, Dietaryaerobic glycolysiskidneymetabolomicssalt dietSprague–Dawley rattranscriptomics

Identifiers

PMID37575482
PMCPMC10413938
OpenAlexW4381799520

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.