Evidence map›Paper›PMID 37576056›Full record

ReviewFood science & nutrition2023

The effectiveness of omega-3 fatty acids on health outcomes in women with breast cancer: A systematic review.

Shirin Osouli-Tabrizi, Amir Mehdizadeh, Mina Naghdi, Zohreh Sanaat, Nafiseh Vahed, Azizeh Farshbaf-Khalili

Open access · hybridAbstract readReview
In one paragraph

Review in Food science & nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shirin Osouli-TabriziDepartment of Midwifery, Faculty of Nursing and Midwifery Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-7984-5043
Amir MehdizadehHematology and Oncology Research Center Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-3029-4172
Mina NaghdiStudent Research Committee, Department of Midwifery, Faculty of Nursing and Midwifery Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-8884-4990
Zohreh SanaatHematology and Oncology Research Center Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-0565-0999
Nafiseh VahedResearch Center for Evidence-based Medicine, Iranian EBM Centre: A Joanna Briggs Institute (JBI) Center of Excellence Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0002-6544-5014
Azizeh Farshbaf-KhaliliPhysical Medicine and Rehabilitation Research Center, Aging Research Institute Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0001-5754-4613
Tabriz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to systematically evaluate the impact of omega-3 fatty acids on the health outcomes of women with breast cancer in electronic databases (PubMed, Scopus, ProQuest, Web of Science, and Cochrane Library) for interventional studies. The risk of bias and the quality of the included articles were assessed by Cochrane Collaboration Handbook guidance. The statistical analyses were not conducted because of the heterogeneity of the included studies. Of 3676 identified articles, 11 articles were included in this study. The majority of the included studies were not of high quality. Median progression time and overall survival significantly improved. Additionally, surgical site healing complications and infection rates decreased. There was a significant decrease in perceived stress, sleep disturbance, depression, pain, joint stiffness, and fatigue throughout the intervention. Moreover, omega-3 fatty acids consumption significantly increased the total serum omega-3, EPA, and DHA, and decreased the omega-6: omega-3 ratio, total leukocytes, lymphocytes, leptin, and CRP, accordingly. Mild gastrointestinal symptoms were reported in only two studies without clinically relevant adverse events. Omega-3 fatty acids may cause improvement in physical, mental, and some inflammatory and metabolic indices during treatment or posttreatment course of breast cancer patients. Due to the possibility of free radical formation, omega-3 FAs supplementation and consumption must be done very carefully.

Indexed as

adjuvant therapybreast cancerhealthOmega‐3 fatty acidssystematic review

Identifiers

PMID37576056
PMCPMC10420771
OpenAlexW4378085744

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.