Evidence mapPaperPMID 37576279Full record

ArticleHeliyon2023

Intrinsic and environmental basis of aging: A narrative review.

Carla Navarro, Juan Salazar, María P Díaz, Maricarmen Chacin, Raquel Santeliz, Ivana Vera, Luis D Marco, Heliana Parra, Mary Carlota Bernal, Ana Castro and 3 more

Abstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Morphology of facial aging: a shape-based quantification.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carla NavarroEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
Juan SalazarEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
María P DíazEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
Maricarmen ChacinUniversidad Simón Bolívar, Facultad de Ciencias de la Salud, Barranquilla 080001, Colombia.
Raquel SantelizEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
Ivana VeraEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
Luis D MarcoUniversidad Cardenal Herrera-CEU Medicine Department, CEU Universities, 46115 Valencia, Spain.
Heliana ParraEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
Mary Carlota BernalUniversidad Simón Bolívar, Facultad de Ingenierías, Cúcuta, Colombia.
Ana CastroEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
Daniel EscalonaEndocrine and Metabolic Diseases Research Center. School of Medicine. University of Zulia. Maracaibo 4001, Venezuela.
Henry García-PachecoUniversidad del Zulia, Facultad de Medicina, Departamento de Cirugía. Hospital General del Sur "Dr. Pedro Iturbe". Maracaibo, Venezuela.
Valmore BermúdezUniversidad Simón Bolívar, Facultad de Ciencias de la Salud, Barranquilla 080001, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Longevity has been a topic of interest since the beginnings of humanity, yet its aetiology and precise mechanisms remain to be elucidated. Aging is currently viewed as a physiological phenomenon characterized by the gradual degeneration of organic physiology and morphology due to the passage of time where both external and internal stimuli intervene. The influence of intrinsic factors, such as progressive telomere shortening, genome instability due to mutation buildup, the direct or indirect actions of age-related genes, and marked changes in epigenetic, metabolic, and mitochondrial patterns constitute a big part of its underlying endogenous mechanisms. On the other hand, several psychosocial and demographic factors, such as diet, physical activity, smoking, and drinking habits, may have an even more significant impact on shaping the aging process. Consequentially, implementing dietary and exercise patterns has been proposed as the most viable alternative strategy for attenuating the most typical degenerative aging changes, thus increasing the likelihood of prolonging lifespan and achieving successful aging.

Indexed as

Age-related genesAgingChronic diseasesObesityTelomeraseTelomeres

Identifiers

PMID37576279
PMCPMC10415626

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.