Evidence map›Paper›PMID 37576322›Full record

ArticleHeliyon2023

Fibrinogen-to-albumin ratios are related to mortality in patients with secondary malignant neoplasm of bone and bone marrow.

Jinsha Zhong

Abstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Fibrinogen and tumors.Frontiers in oncology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Jinsha ZhongDepartment of Clinical Laboratory, Affiliated Jinhua Hospital Zhejiang University School of Medicine, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Systemic inflammation has long been considered to be one of the mechanisms in the development and progression of secondary malignant neoplasm of bone and bone marrow (BM). Fibrinogen-to-albumin ratio (FAR) has been demonstrated to be vital to the poor prognosis of lots of disease such as tumor and coronary heart disease. This study aimed to determine whether FAR could be used as an independent risk prognostic factor in patients with BM. Methods: Firstly, the baseline data of patients with BM, who met our inclusion/exclusion criteria, were extracted and analyzed from MIMIC-III database. The association between FAR and endpoints was analyzed using a Cox proportional hazards regression model and a propensity score matched analysis. Results: The univariate analysis revealed that for the 30-day mortality, the HR (95% CI) in the FAR ≥99.5group was 1.47 (1.15,1.91). After adjusting various factors, FAR ≥99.5 was found to be an independent significant risk factor for death in patients with BM (HR = 1.11, 95% CI: 1.01-1.42). Similarly, for the one-year mortality, HR (95% CI) in the FAR ≥99.5 group was 1.51 (1.11, 2.06). Conclusion: It has been found that FAR provides independent prognostic information for mortality among patients with secondary malignant neoplasms of the bone and bone marrow.

Indexed as

Fibrinogen-to-albumin ratioInflammationMortalityPrognostic factorSecondary malignant neoplasm of bone and bone marrow

Identifiers

PMID37576322
PMCPMC10415879

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.