ReviewJournal of pain research2023
Nonpharmacological Interventions for Management of the Pain-Fatigue-Sleep Disturbance Symptom Cluster in Breast Cancer Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
Review in Journal of pain research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07061028 (The Effects of Progressive Muscle Relaxation on Pain Intensity, Pain Catastrophizing, and Quality of Life in Patients With End Stage Renal Disease), which is not on this map. Cited by 20 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Progressive Muscle Relaxation on Pain Intensity, Pain Catastrophizing, and Quality of Life in Patients With End Stage Renal Disease: A Randomized Controlled Study
Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Effects of different mind-body exercises on quality of life and cancer-related fatigue in breast cancer survivors: a systematic review and network meta-analysis.Journal of cancer survivorship : research and practice · 2026Pooled it
- Exercise and mind-body therapies for fatigue in breast cancer: evidence mapping from systematic reviews.BMJ supportive & palliative care · 2026Pooled it
- Effects of using app-based interventions on quality of life among breast cancer patients: a systematic review with meta-analysis.Annals of medicine · 2025Pooled it
- Effectiveness of ePRO-based symptom management for cancer patients: a systematic review and meta-analysis of randomized controlled studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Efficacy of non-pharmacological interventions on sleep quality in patients with cancer-related insomnia: a network meta-analysis.Frontiers in neurology · 2024Pooled it
- Identification of Symptom Profiles in Prostate Cancer Survivors.Oncology nursing forum · 2025Trial
- Non-pharmacological sleep management in breast cancer survivors: Evidence from a systematic review and meta-analysis of RCTs.Preventive medicine reports · 2026Review
- The interplay of circadian rhythms and cancer pain: a narrative review.Journal of anesthesia, analgesia and critical care · 2026Review
- Healing the Mind to Ease Pain and Fatigue: The Role of Attachment, Mindfulness, and Cognitive Emotion Regulation in Early-Stage Breast Cancer Survivors.Cancer reports (Hoboken, N.J.) · 2026Article
- Latent profile analysis for assessing symptom clusters in women with breast cancer.Journal of cancer survivorship : research and practice · 2026Article
- Evaluating an educational supportive care program on functional status and quality of life among women with breast cancer post-mastectomy in Egypt.Palliative care and social practice · 2026Article
- Comparing Massage, Acupressure, and Combined Therapy for Managing Cancer-related Pain, Fatigue, and Sleep Disturbance: A 2 × 2 Factorial Randomized Controlled Trial.International journal of therapeutic massage & bodywork · 2025Article
- Construction and validation of a risk-prediction model for chemotherapy-related cognitive impairment in patients with breast cancer.Journal of cancer survivorship : research and practice · 2025Observational
- Article
- Detection of differences in physical symptoms between depressed and undepressed patients with breast cancer: a study using K-medoids clustering.BMC cancer · 2025Article
- A Review of Novel Cancer Therapeutics and Current Research Trends.TheScientificWorldJournal · 2025Review
- Acupuncture for the treatment of the pain-fatigue-sleep disturbance-numbness/tingling symptom cluster in breast cancer survivors: a feasibility trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Effects of nonpharmacological interventions on symptom clusters in breast cancer survivors: A systematic review of randomized controlled trials.Asia-Pacific journal of oncology nursing · 2024Review
- Symptom Clusters and Their Impact on Spiritual Well-Being Among Women with Breast Cancer.International journal of women's health · 2024Article
- Postoperative screening for distress symptom cluster in patients with pituitary adenomas: a propensity-score matched outcome analysis.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The pain-fatigue-sleep disturbance symptom cluster is commonly experienced by breast cancer patients, and a variety of nonpharmacological interventions are used to treat this symptom cluster. Objective: To compare the efficacy of nonpharmacological interventions in improving the symptoms of the pain-fatigue-sleep disturbance symptom cluster in breast cancer patients. Methods: A comprehensive literature search was conducted in the PubMed, EMBASE, Cochrane Library, CINAHL, CNKI, and Wanfang databases to identify randomized controlled studies from database inception to May 2022. Two reviewers independently performed data retrieval and risk of bias assessments. The consistency model was used to conduct network meta-analyses (NMA) based on the frequentist framework to assess the interventions, which were ranked by the surface under the cumulative ranking curve (SUCRA). Finally, the CINeMA application was used to evaluate the results of the NMA and the evidence of quality. The results Twenty-three eligible studies assessing 14 interventions were included. According to SUCRA values, among the management effects of the three symptoms, the effect of progressive muscle relaxation (PMR) ranked first, followed by mindfulness-based stress reduction (MBSR). The overall evidence quality of our study ranges from very low to moderate. Conclusion: PMR and MBSR were effective interventions for the pain-fatigue-sleep disturbance symptom cluster in breast cancer patients. Clinical recommendations prioritize PMR for symptom management, followed by MBSR. However, this should be interpreted cautiously, as the confidence in the evidence was not high.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.