Evidence map›Paper›PMID 37577463›Full record

ArticlebioRxiv : the preprint server for biology2023

A molecular atlas of adult

Jayson J Smith, Seth R Taylor, Jacob A Blum, Aaron D Gitler, David M Miller, Paschalis Kratsios

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jayson J SmithDepartment of Neurobiology, University of Chicago, Chicago, IL, 60637, USA.
Seth R TaylorDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA.
Jacob A BlumDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Aaron D GitlerDepartment of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
David M MillerDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA.
Paschalis KratsiosDepartment of Neurobiology, University of Chicago, Chicago, IL, 60637, USA.
Stanford University · USUniversity of Chicago · USBrigham Young University · USVanderbilt University · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI KUNLE ODUNSI · 1985 to 2026
$122.1M
Training Program in Basic NeuroscienceT32MH020016 · NIMH · STANFORD UNIVERSITY · PI Justin L Gardner, Merritt C Maduke · 1997 to 2026
$16.2M
Discovery and analysis of the C. elegans neuronal gene expression network (CENGEN)R01NS100547 · NINDS · YALE UNIVERSITY · PI MARC HAMMARLUND, Oliver Hobert · 2017 to 2026
$11.2M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Molecular Genetics of Synaptic PlasticityR01NS106951 · NINDS · VANDERBILT UNIVERSITY · PI BIANCHI, LAURA, MILLER, DAVID M · 2018 to 2022
$2.2M
Hox-dependent mechanisms for establishment and maintenance of motor neuron terminal identityR01NS116365 · NINDS · UNIVERSITY OF CHICAGO · PI KRATSIOS, PASCHALIS · 2020 to 2024
$2.0M
Molecular mechanisms for neuron-specific assembly of electrical synapsesR01NS113559 · NINDS · VANDERBILT UNIVERSITY · PI MILLER, DAVID M · 2020 to 2024
$1.8M
Molecular mechanisms of motor neuron terminal identityR01NS118078 · NINDS · UNIVERSITY OF CHICAGO · PI KRATSIOS, PASCHALIS · 2020 to 2024
$1.8M
Identification of the transcriptional targets of three conserved regulatory factors necessary for motor neuron subtype function - Resubmission 01R21NS108505 · NINDS · UNIVERSITY OF CHICAGO · PI KRATSIOS, PASCHALIS, MILLER, DAVID M · 2019 to 2019
$442k
NCI NIH HHS P30 CA014599NIH HHS P40 OD010440NIMH NIH HHS T32 MH020016NINDS NIH HHS R01 NS100547NINDS NIH HHS R01 NS106951NINDS NIH HHS R01 NS113559NINDS NIH HHS R01 NS116365NINDS NIH HHS R01 NS118078NINDS NIH HHS R21 NS108505
6 · The paper itself

Abstract

Motor neurons (MNs) constitute an ancient cell type targeted by multiple adult-onset diseases. It is therefore important to define the molecular makeup of adult MNs in animal models and extract organizing principles. Here, we generated a comprehensive molecular atlas of adult

Indexed as

adult motor neuronsC. elegansHox genesneuropeptidesscRNA-seqtranscription factors

Identifiers

PMID37577463
PMCPMC10418256
OpenAlexW4385612177

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.