Evidence map›Paper›PMID 37577625›Full record

ArticlebioRxiv : the preprint server for biology2025

Ciliary ARL13B is essential for body weight regulation in adult mice.

Tiffany T Terry, Eduardo D Gigante, Coralie M Alexandre, Kathryn M Brewer, Xinyu Yue, Nicolas F Berbari, Christian Vaisse, Tamara Caspary

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Tiffany T TerryDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-2729-6281
Eduardo D GiganteDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-1486-5377
Coralie M AlexandreDiabetes Center and Department of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0009-0004-2978-2648
Kathryn M BrewerDepartment of Biology, Indiana University- Indianapolis, Indianapolis, IN, USA.ORCID 0009-0006-3498-4492
Xinyu YueDiabetes Center and Department of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-6187-5906
Nicolas F BerbariDepartment of Biology, Indiana University- Indianapolis, Indianapolis, IN, USA.ORCID 0000-0003-2863-1069
Christian VaisseDiabetes Center and Department of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-4274-7033
Tamara CasparyDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-6579-7589
University of California, San Francisco · USEmory University · USUniversity of Indianapolis · USGeorgia Institute of Technology · US

Funding

UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
The Melanocortin-4 Receptor in Human ObesityR01DK060540 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2002 to 2026
$7.5M
Obesity in Ciliopathies: How Neuronal Primary Cilia Control AppetiteR01DK106404 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REITER, JEREMY F, VAISSE, CHRISTIAN · 2016 to 2025
$6.6M
Training In Systems And Integrative Biology NeuroscienceT32NS096050 · NINDS · EMORY UNIVERSITY · PI Yoland Smith · 2016 to 2026
$3.9M
Functional characterization of obesity-associated OXTR enhancersR01DK124769 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, VAISSE, CHRISTIAN · 2020 to 2024
$3.7M
How Hedgehog Contributes to Centrally Mediated Energy Homeostasis?R01DK114008 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Nicolas F Berbari, Jeremy F Reiter · 2018 to 2026
$3.3M
Genetic Dissection of Signaling and CiliaR35GM148416 · NIGMS · EMORY UNIVERSITY · PI TAMARA J. CASPARY · 2023 to 2026
$2.1M
Genetic Dissection of Signaling and CiliaR35GM122549 · NIGMS · EMORY UNIVERSITY · PI CASPARY, TAMARA J. · 2017 to 2021
$2.0M
Mechanisms underlying Joubert syndrome related brain malformationsR01NS090029 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ANTON, EVA S, CASPARY, TAMARA J. · 2015 to 2018
$1.9M
The Critical Role of Ciliary ARL13B in Controlling Energy HomeostasisF32DK137409 · NIDDK · EMORY UNIVERSITY · PI Tiffany T Terry · 2024 to 2026
$249k
Defining the relationship of ciliary Arl13b and SmoothenedF31NS106755 · NINDS · EMORY UNIVERSITY · PI GIGANTE, EDUARDO D. · 2019 to 2020
$91k
Cilia-mediated Proliferation in Hypothalamic TanycytesF31DK142351 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Kathryn M Brewer · 2025 to 2026
$82k
NIDDK NIH HHS F31 DK142351NIDDK NIH HHS F32 DK137409NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK060540NIDDK NIH HHS R01 DK106404NIDDK NIH HHS R01 DK114008NIDDK NIH HHS R01 DK124769NIGMS NIH HHS R35 GM122549NIGMS NIH HHS R35 GM148416NINDS NIH HHS F31 NS106755NINDS NIH HHS R01 NS090029NINDS NIH HHS T32 NS096050
6 · The paper itself

Abstract

Cilia are near ubiquitous cellular appendages critical for cell-to-cell communication and involved in diverse developmental and homeostatic processes. ARL13B is a regulatory GTPase enriched in cilia. We engineered an

Indexed as

ARL13Bciliaenergy homeostasishyperphagiaobesity

Identifiers

PMID37577625
PMCPMC10418222
OpenAlexW4385797977

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.