Evidence mapPaperPMID 37577812Full record

ReviewClimacteric : the journal of the International Menopause Society2024

Vasomotor symptoms and cardiovascular health: findings from the SWAN and the MsHeart/MsBrain studies.

R C Thurston

Open access · greenAbstract readReview
In one paragraph

Review in Climacteric : the journal of the International Menopause Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Hot flashes and sleep disruption in a randomized trial in menopausal women.American journal of obstetrics and gynecology · 2025
    Trial
  3. Review
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

R C ThurstonDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
University of Pittsburgh · US

Funding

The Study of Women's Health Across the Nation (SWAN): The Impact of Midlife and the Menopause Transition on Health and Functioning in Early Old AgeU19AG063720 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Maria Mori Brooks · 2024 to 2024
$21.9M
WOMENS HEALTH ACROSS THE NATION--PITTSBURGHU01AG012546 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1994 to 2005
$8.4M
WOMENS HEALTH ACROSS THE NATION--COORDINATING CENTERU01AG012553 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1994 to 2005
$7.8M
WOMENS HEALTH ACROSS THE NATION--ENDOCRINE LABU01AG012495 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 1994 to 2005
$7.4M
WOMENS HEALTH ACROSS THE NATION--UCDAVISU01AG012554 · UNIVERSITY OF CALIFORNIA DAVIS · 1994 to 2005
$4.5M
WOMENS HEALTH ACROSS THE NATION--UCLAU01AG012539 · UNIVERSITY OF CALIFORNIA LOS ANGELES · 1994 to 2005
$4.5M
WOMENS HEALTH ACROSS THE NATION--CHICAGOU01AG012505 · RUSH UNIVERSITY MEDICAL CENTER · 1994 to 2005
$4.4M
Women's Health Across the Nation-New Jersey SiteU01AG012535 · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · 1994 to 2005
$4.0M
THE STUDY OF WOMEN'S HEALTH ACROSS THE NATION-MICHIGANU01NR004061 · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 1994 to 2005
$4.0M
WOMENS HEALTH ACROSS THE NATION--MASSACHUSETTS GENERAL HU01AG012531 · MASSACHUSETTS GENERAL HOSPITAL · 1994 to 2005
$3.3M
Menopausal Vasomotor Symptoms and Brain Aging in WomenR01AG053504 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2025 to 2025
$760k
Interdisciplinary Mentoring and Research in Womens Cardiovascular HealthK24HL123565 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REBECCA C THURSTON · 2023 to 2023
$112k
NCATS NIH HHS UL1 TR000005NCRR NIH HHS S10 RR023461NHLBI NIH HHS K24 HL123565NHLBI NIH HHS R01 HL105647NIA NIH HHS R01 AG053504NIA NIH HHS RF1 AG053504NIA NIH HHS U01 AG012495NIA NIH HHS U01 AG012505NIA NIH HHS U01 AG012531NIA NIH HHS U01 AG012535NIA NIH HHS U01 AG012539NIA NIH HHS U01 AG012546NIA NIH HHS U01 AG012553NIA NIH HHS U01 AG012554NIA NIH HHS U19 AG063720NINR NIH HHS U01 NR004061
6 · The paper itself

Abstract

Vasomotor symptoms (VMS) are often considered the classic menopausal symptom and are experienced by most women during the menopause transition. VMS are well established to be associated with decrements in quality of life during the menopause. More recent research also links VMS to poorer cardiovascular health. This review summarizes key insights about links between VMS and cardiovascular disease (CVD) risk that come from the Study of Women's Health Across the Nation (SWAN), a longitudinal epidemiologic cohort study of the menopause transition, as well as from the MsHeart/MsBrain studies, clinical studies that leverage vascular imaging and brain imaging as well as wearable technologies that provide objective indicators of VMS. Using a range of methodologies and extensive consideration of confounders, these studies have shown that frequent and/or persistent VMS are associated with adverse CVD risk factor profiles, poorer underlying peripheral vascular and cerebrovascular health, and elevated risk for clinical CVD events. Collectively, the SWAN and MsHeart/MsBrain studies form complementary epidemiologic and clinical studies that point to the importance of VMS to women's cardiovascular health during the menopause transition and beyond.

Indexed as

Cardiovascular DiseasesHot FlashesCohort StudiesFemaleHumansLongitudinal StudiesMenopauseQuality of LifeSweatingVasomotor SystemWomen's Healthatherosclerosiscardiovascular diseasecerebrovascular diseaseendothelial functionheart attackhot flasheshot flushesstrokeVasomotor symptoms

Identifiers

PMID37577812
PMCPMC10843629
OpenAlexW4385798784

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.