ArticlePublic health nutrition2023
Identifying optimal ranges of weight gain at the end of the second trimester result from a population-based cohort study.
Article in Public health nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- Late Preschool BMI Acceleration as the Strongest Predictor of Childhood Cardiometabolic Risk at School Entry: A Dual-Trajectory Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Real-world evaluation of Chinese National Maternal and Newborn Safety Action Plan for reducing neonatal mortality among pregnant women with conditions: a retrospective, matched, population-based cohort study.BMJ public health · 2026Article
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9 authors at 4 institutions in 1 country.
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Abstract
objectiveTo identify the optimal weight gain at the end of the second trimester.
designThis was a population-based cohort study from the antenatal care system in Tianjin, China. We calculated gestational weight gain (GWG) based on the weight measured in the first trimester and the end of the second trimester. Restricted cubic spline analysis was performed to model the possible non-linear relationships between GWG and adverse outcomes. The optimal GWG was defined as the value of the lowest risk. Non-inferiority margins and the shape of the spline curves identified the recommended ranges in Chinese-specific BMI categories.
settingTianjin Maternal and Child Health Cohort.
participantsSingleton pregnant women aged 18-45 years.
resultsIn total, 69 859 pregnant women were included. Adverse outcome (including stillbirth, preterm birth, hypertensive disorders of pregnancy, gestational diabetes mellitus, small and large for gestational age) was significantly associated with GWG at the end of the second trimester. The risk score was non-linearly correlated with GWG in the underweight, normal weight and overweight groups. GWG at the end of the second trimester should not be < 7 kg in underweight group. For most normal-weight women, a GWG of about 8 kg is optimal. Pregnant women who are overweight should not have a GWG of more than 9 kg. We advised women with overweight and obesity to keep positive growth of GWG (> 0 kg) in the first and second trimesters.
conclusionsAccording to the comprehensive adverse maternal and infant outcomes, we recommend the optimal GWG at the end of the second trimester. This study may provide a considerable reference for weight management.
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