Evidence map›Paper›PMID 37579875›Full record

ArticleThe journal of allergy and clinical immunology. In practice2023

Progestogen Hypersensitivity.

Sergio E Chiarella, Kathleen M Buchheit, Dinah Foer

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Autoimmune progesterone dermatitis: diagnostic relevance and epidemiological analysis of 13 cases.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sergio E ChiarellaDivision of Allergic Diseases, Mayo Clinic, Rochester, Minn. Electronic address: Chiarella.Sergio@mayo.edu.
Kathleen M BuchheitDivision of Allergy and Clinical Immunology, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Dinah FoerDivision of Allergy and Clinical Immunology, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Brigham and Women's Hospital · USMayo Clinic · US

Funding

The Role of IL-5 and Local Nasal Polyp Immunoglobulin Production in Aspirin-Exacerbated Respiratory DiseaseK23AI139352 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BUCHHEIT, KATHLEEN MARY · 2019 to 2023
$1.0M
Effects of GLP-1 Receptor Agonists on Airway Inflammation and Platelet Activation in AsthmaK23HL161332 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Dinah Foer · 2022 to 2026
$975k
Gender-specific effects of puberty on airway epithelial differentiation in asthmaK08AI141765 · NIAID · MAYO CLINIC ROCHESTER · PI CHIARELLA, SERGIO E · 2019 to 2023
$929k
NHLBI NIH HHS K23 HL161332NIAID NIH HHS K08 AI141765NIAID NIH HHS K23 AI139352
6 · The paper itself

Abstract

Progestogen hypersensitivity (PH) is a heterogeneous disease characterized by diverse cutaneous manifestations, bronchospasm, and/or anaphylaxis. Possible triggers include ovarian progesterone and exogenous progestogens. The timing of symptoms is critical to diagnose PH: during the luteal phase of the menstrual cycle for the endogenous form and after exposure to progestins for exogenous PH. Diagnostic modalities such as progesterone skin testing have low sensitivity and specificity for PH. When exogenous PH is suspected, the allergist should consider a progestogen challenge. Treatment strategies should be tailored for each patient, including symptom-directed therapies, ovulation suppression, and progesterone desensitization. Future studies should explore the mechanisms of PH, validation of diagnostic criteria, and standardization of treatment strategies.

Indexed as

AnaphylaxisProgestinsDesensitization, ImmunologicFemaleHumansMenstrual CycleProgesteroneProgesteroneProgestinsAutoimmune progesterone dermatitisEndocrine allergyInfertilityMenstrual cycleProgesteroneProgestinSteroid hormone allergy

Identifiers

PMID37579875
PMCPMC10841326
OpenAlexW4385780011

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.