Evidence mapPaperPMID 37581339Full record

ReviewGenes, brain, and behavior2023

The collaborative study on the genetics of alcoholism: Sample and clinical data.

Danielle M Dick, Emily Balcke, Vivia McCutcheon, Meredith Francis, Sally Kuo, Jessica Salvatore, Jacquelyn Meyers, Laura J Bierut, Marc Schuckit, Victor Hesselbrock and 6 more

Open access · hybridAbstract readReview
In one paragraph

Review in Genes, brain, and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  9. A Multivariate Genomic Investigation of the Externalizing Spectrum and Suicide Risk.medRxiv : the preprint server for health sciences · 2025
    Article
  10. Article
  11. Childhood Trauma andmedRxiv : the preprint server for health sciences · 2025
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 1 country.

Danielle M DickDepartment of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.ORCID 0000-0002-1636-893X
Emily BalckeDepartment of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Vivia McCutcheonDepartment of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Meredith FrancisSchool of Social Work, Virginia Commonwealth University, Richmond, Virginia, USA.
Sally KuoDepartment of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.ORCID 0000-0002-6192-1001
Jessica SalvatoreDepartment of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Jacquelyn MeyersDepartment of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Laura J BierutDepartment of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.
Marc SchuckitDepartment of Psychiatry, University of California San Diego School of Medicine, La Jolla, California, USA.
Victor HesselbrockDepartment of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Howard J EdenbergDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Bernice PorjeszDepartment of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
COGA Collaborators
Samuel KupermanDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
John KramerDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Kathleen BucholzDepartment of Psychiatry, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0003-3794-0736
Rutgers, The State University of New Jersey · USUniversity of Iowa · USWashington University in St. Louis · USSUNY Downstate Health Sciences University · USIndiana University School of MedicineUniversity of California San Diego · USUniversity of Connecticut · USVirginia Commonwealth University · US

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JAY Arnold TISCHFIELD · 1989 to 2026
$162.7M
NIAAA NIH HHS U10 AA008401NIAAA NIH HHS U10AA008401
6 · The paper itself

Abstract

The collaborative study on the genetics of alcoholism (COGA) is a multi-site, multidisciplinary project with the goal of identifying how genes are involved in alcohol use disorder and related outcomes, and characterizing how genetic risk unfolds across development and in conjunction with the environment and brain function. COGA is a multi-generational family-based study in which probands were recruited through alcohol treatment centers, along with a set of community comparison families. Nearly 18,000 individuals from >2200 families have been assessed over a period of over 30 years with a rich phenotypic battery that includes semi-structured psychiatric interviews and questionnaire measures, along with DNA collection and electrophysiological data on a large subset. Participants range in age from 7 to 97, with many having longitudinal assessments, providing a valuable opportunity to study alcohol use and problems across the lifespan. Here we provide an overview of data collection methods for the COGA sample, and details about sample characteristics and comorbidity. We also review key research findings that have emerged from analyses of the COGA data. COGA data are available broadly to researchers, and we hope this overview will encourage further collaboration and use of these data to advance the field.

Indexed as

AlcoholismAlcohol DrinkingHumansRisk Factorsalcoholcomorbiditydevelopmentdrugenvironmentgeneticslifespan

Identifiers

PMID37581339
PMCPMC10550787
OpenAlexW4385827455

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.