Evidence map›Paper›PMID 37582244›Full record

ArticleAnalytical chemistry2023

Improving Quantitative Accuracy in Nontargeted Lipidomics by Evaluating Adduct Formation.

Lauren M Bishop, Tong Shen, Oliver Fiehn

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  3. Review
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  8. Article
  9. The lipidome of posttraumatic stress disorder.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lauren M BishopDepartment of Chemistry, University of California Davis, Davis, California 95616, United States.
Tong ShenWest Coast Metabolomics Center, 451 Health Sci. Drive, University of California Davis, Davis, California 95616, United States.
Oliver FiehnWest Coast Metabolomics Center, 451 Health Sci. Drive, University of California Davis, Davis, California 95616, United States.ORCID 0000-0002-6261-8928
University of California, Davis · US

Funding

Systems BiologyU19AG023122 · NIA · TRANSLATIONAL GENOMICS RESEARCH INST · PI PAOLA SEBASTIANI · 2004 to 2026
$102.6M
Lp(a) and Oxidized Phospholipids - Impact of DietsR01HL157535 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BYAMBAA, ENKHMAA · 2022 to 2025
$2.4M
NHLBI NIH HHS R01 HL157535NIA NIH HHS U19 AG023122
6 · The paper itself

Abstract

For large-scale lipidomic analyses, accurate and reproducible quantification of endogenous lipids is crucial for comparing results within and across studies. Many lipids present in liquid chromatography-electrospray ionization-mass spectrometry form various adducts with buffer components. The mechanisms and conditions that dictate adduct formation are still poorly understood. In a positive mode, neutral lipids like mono-, di-, and triacylglycerides and cholesteryl esters typically generate [M + NH

Indexed as

LipidomicsSpectrometry, Mass, Electrospray IonizationAnimalsChromatography, LiquidIonsLiverMiceSodiumIonsSodium

Identifiers

PMID37582244
PMCPMC11639661
OpenAlexW4385829792

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.