ArticleBMC public health2023
Waist-to-height ratio associated cardiometabolic risk phenotype in children with overweight/obesity.
Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Improving National Fitness: An Updated Review on Cardiovascular Disease Risk Screening and Exercise Training in School-Aged Children in the U.S.Current cardiology reports · 2026Review
- Metabolic score for visceral fat: a novel tool for assessing stroke risk in middle-aged and elderly Chinese adults - evidence from the CHARLS cohort study.BMC neurology · 2026Article
- Article
- What Shapes Quality of Life in Youth? A Multidimensional Approach from Lifestyle to Residential Context-Cor-School Study.Healthcare (Basel, Switzerland) · 2025Article
- Review
- Effect of obesity on cardiovascular morphofunctional phenotype: Study of Mendelian randomization.Medicine · 2025Article
- Five-repetition sit-to-stand test validation in adolescents and adults with intellectual disabilities.Scientific reports · 2024Article
- Genome-wide discovery and integrative genomic characterization of insulin resistance loci using serum triglycerides to HDL-cholesterol ratio as a proxy.Nature communications · 2024Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundChildhood overweight/obesity has been associated with an elevated risk of insulin resistance and cardiometabolic disorders. Waist-to-height ratio (WHtR) may be a simple screening tool to quickly identify children at elevated risk for cardiometabolic disorders. The primary objective of the present study was to create sex-specific tertile cut points of WHtR and assess its association with Insulin resistance and elevated liver enzyme concentrations in children, factors using cross-sectional data from the randomized, controlled Family Weight Management Study.
methodsBaseline data from 360 children (7-12 years, mean Body Mass Index (BMI) ≥ 85
resultsStudy participants had a mean WHtR of 0.59 ([SD: 0.06]). Irrespective of sex, children in WHtR T3 had higher BMIz scores, blood pressure, triglycerides, 2-h glucose, fasting 2-h insulin, and lower high-density lipoprotein cholesterol (HDL-C) concentrations than those in T2 and T1. After adjusting for covariates, the odds of elevated HOMA-IR (> 2.6) were over five-fold higher among males in T3 versus T1 [OR, 95%CI: 5.83, 2.34-14.52] and T2 [OR, 95%CI: 4.81, 1.94-11.92] and females in T3 [OR, 95%CI: 5.06, 2.10-12.20] versus T1. The odds of elevated ALT values (≥ 30) were 2.9 [95%CI: 1.01-8.41] fold higher among females in T3 compared to T1.
conclusionIn public health settings, WHtR may be a practical screening tool in pediatric populations to identify children at risk of metabolic syndrome.
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