ArticlePhysical activity and nutrition2023
Effect of high-dose vitamin C and E supplementation on muscle recovery and training adaptation: a mini review.
Article in Physical activity and nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Similar Muscle Recovery but Greater Soreness in Active Vegans on Low-Protein Diets Compared to High-Protein Omnivores Following Exercise-Induced Damage.Nutrition bulletin · 2026Article
- Epigenetic Modulation of Exercise Adaptation: The Role of Dietary Supplementation in Athletic Performance.Genes · 2026Review
- Muscle loss and GLP-1R agonists use.Acta diabetologica · 2026Review
- Review
- Potential Vitamin E Signaling Mediators in Skeletal Muscle.Antioxidants (Basel, Switzerland) · 2024Review
- Youth and Adolescent Athlete Musculoskeletal Health: Dietary and Nutritional Strategies to Optimise Injury Prevention and Support Recovery.Journal of functional morphology and kinesiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis review aimed to investigate the effects of high-dose vitamins C and E supplementation combined with acute or chronic exercise on muscle recovery and training adaptation.
methodsWe used PubMed, Web of Science, and Wiley Online Library databases to perform a literature search based on the keywords 'vitamin C, vitamin E, antioxidants, muscle recovery, training adaptation, and oxidative stress'.
resultsVitamin C or E supplementation has been reported to contribute to a reduction in oxidative stress and muscle damage; however, there is currently inadequate evidence of their positive effects on muscle recovery. Long-term vitamin C or E supplementation can have negative effects on physiological phenomena required for training adaptation, such as strength, muscle hypertrophy, and endurance. Numerous studies emphasized that an adequate diet consisting of fruits and vegetables is a more appropriate way of consuming antioxidants than supplementation.
conclusionThe effects of high-dose vitamin C and E supplementation on post-exercise muscle recovery remain unclear and ambiguous, although there is evidence of potential negative effects on training adaptation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.