Evidence map›Paper›PMID 37588008›Full record

ReviewJournal of osteoporosis2023

Additive Effects of Exercise and Vitamin D Supplementation (with and without Calcium) on Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis.

Cecilie Fischer, Franz Jakob, Matthias Kohl, Stephanie Kast, Simon Von Stengel, Katharina Kerschan-Schindl, Uwe Lange, Friederike Thomasius, Stefan Peters, Michael Uder and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of osteoporosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Cecilie FischerInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.
Franz JakobBernhard-Heine-Centrum für Bewegungsforschung, University of Würzburg, Würzburg, Germany.
Matthias KohlDepartment of Medical and Life Sciences, University of Furtwangen, Schwenningen, Germany.ORCID https://orcid.org/0000-0001-9514-8910
Stephanie KastInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.
Simon Von StengelInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.
Katharina Kerschan-SchindlAustrian Society for Bone and Mineral Research, Vienna, Austria.
Uwe LangeGerman Society for Physical and Rehabilitative Medicine, Ulm, Germany.
Friederike ThomasiusOsteology Umbrella Association Germany, Austria, Switzerland, Germany.
Stefan PetersGerman Association for Health-Related Fitness and Exercise Therapy (DVGS) e.V., Hürth-Efferen, Germany.
Michael UderInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.
Wolfgang KemmlerInstitute of Radiology, University Hospital Erlangen, Erlangen, Germany.ORCID https://orcid.org/0000-0003-3515-0669
Universitätsklinikum Erlangen · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEFurtwangen University · DEGerman Insurance Association · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise is a recognized component in the prevention and therapy of osteoporosis. The present systematic review and meta-analysis aimed to determine the effect of Vitamin D (Vit-D) added to exercise versus exercise alone on bone mineral density (BMD) at the lumbar spine (LS) or hip in older adults. A systematic review based on six literature databases according to PRISMA included (a) exercise trials, with an exercise (EX) and a combined exercise + Vit-D group (EX + Vit-D), (b) intervention ≥ 6 months, and (c) BMD assessments at LS or hip. Effects sizes (MD) and 95%-confidence intervals (95%-CI) were calculated using a random-effect model that includes the inverse heterogeneity model (IVhet). Five studies with 281 participants in the EX and 279 participants in the EX + Vit-D were included. No significant differences between EX versus EX + Vit-D were observed for BMD-LS (MD: 0.002, 95%-CI: -0.033 to 0.036) or BMD-hip (MD: 0.003, 95%-CI: -0.035 to 0.042). Heterogeneity between the trial results was moderate-substantial for LS (

Identifiers

PMID37588008
PMCPMC10427236
OpenAlexW4385649883

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.