Evidence map›Paper›PMID 37588314›Full record

ReviewCureus2023

The Prospect of Non-Alcoholic Fatty Liver Disease in Adult Patients with Metabolic Syndrome: A Systematic Review.

Zareen Zohara, Ademiniyi Adelekun, Kofi D Seffah, Korlos Salib, Lana Dardari, Maher Taha, Purva Dahat, Stacy Toriola, Travis Satnarine, Ana P Arcia Franchini

Abstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Geographic Liver.Cureus · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zareen ZoharaResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ademiniyi AdelekunResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Kofi D SeffahResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Korlos SalibResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Lana DardariResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Maher TahaResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Purva DahatResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Stacy ToriolaResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Travis SatnarineResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ana P Arcia FranchiniResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, there has been an increasing trend in the development of non-alcoholic fatty liver disease (NAFLD) due to lifestyle changes. The limited treatment option for the disease makes it challenging to manage. This study aims to summarize the relationship between NAFLD and metabolic syndrome (MetS) and to give a clear idea of the risk factors in this systematic research. The five databases screened were PubMed, Google Scholar, Science Direct, and BMC using keywords and Medical Subject Heading (Mesh) combinations. The keywords used are "Metabolic Syndrome," "Syndrome X," "Insulin Resistance," "Obesity," "Type 2 Diabetes," and "Dyslipidemia." Articles underwent a detailed process of screening and quality appraisal. Using the English language as a primary filtering parameter, papers over the last 13 years, dating from 2010 to 2023, are the basis of this review. We reviewed all possible human studies documenting NAFLD with a component of MetS. A total of 1106 papers were identified. After duplicate removal, 995 articles underwent a rigorous review, and 35 articles were chosen for quality appraisal. A total of 15 articles are part of this systematic review. This systematic review strongly concludes that NAFLD predominates in MetS patients. The pathophysiology and insulin resistance that is shared by the two conditions as well as the fact that obesity is at the center of both is the connecting factor in this. Besides various demographic and risk factors, physical activity and diet also play a role in the development of NAFLD. Consequently, more studies on this relevant topic are needed.

Indexed as

dyslipidemiainsulin resistancemetabolic syndromeobesitysyndrome xtype 2 diabetes

Identifiers

PMID37588314
PMCPMC10427027

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.