Evidence map›Paper›PMID 37592763›Full record

ArticleCell cycle (Georgetown, Tex.)2023

SNTB1 regulates colorectal cancer cell proliferation and metastasis through YAP1 and the WNT/β-catenin pathway.

Hao Zhang, Zheng Li, Juan Jiang, Yang Lei, Jingmao Xie, Yihui Liu, Bo Yi

Open access · greenAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
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  9. Unleashing Wnts: Wnt Ligands Fuel Cancer Spread.Journal of cancer biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hao ZhangDepartment of Gastrointestinal Surgery, the Third Xiangya Hospital, Central South University, Changsha, China.
Zheng LiDepartment of Gastrointestinal Surgery, the Third Xiangya Hospital, Central South University, Changsha, China.
Juan JiangDepartment of Nephrology, the Third Xiangya Hospital, Central South University, Changsha, China.
Yang LeiDepartment of Gastrointestinal Surgery, the Third Xiangya Hospital, Central South University, Changsha, China.
Jingmao XieDepartment of Gastrointestinal Surgery, the Third Xiangya Hospital, Central South University, Changsha, China.
Yihui LiuDepartment of Gastrointestinal Surgery, the Third Xiangya Hospital, Central South University, Changsha, China.
Bo YiDepartment of Gastrointestinal Surgery, the Third Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNThird Xiangya Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer is a common type of digestive tract cancer with a significant morbidity and death rate across the world, partially attributing to the metastasis-associated problems. In this study, integrative bioinformatics analyses were performed to identify genes that might contribute to colorectal cancer metastasis, and 293 genes were dramatically increased and 369 genes were decreased within colon cancer samples. Among up-regulated genes, top five genes correlated with colorectal cancer patient's prognosis were verified for expression in clinical samples and syntrophin beta 1 (SNTB1) was the most up-regulated.

Indexed as

beta CateninColorectal NeoplasmsDystrophin-Associated ProteinsAnimalsCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansMiceMice, NudeProto-Oncogene Proteins c-mycWnt Signaling PathwayYAP-Signaling Proteinsbeta CateninDystrophin-Associated ProteinsProto-Oncogene Proteins c-mycSNTB1 protein, humanYAP1 protein, humanYAP-Signaling ProteinsColorectal cancermetastasisSNTB1the Wnt/β-catenin/MYC signalingYAP1

Identifiers

PMID37592763
PMCPMC10599191
OpenAlexW4385969514

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.