Evidence map›Paper›PMID 37594175›Full record

ArticleActa obstetricia et gynecologica Scandinavica2023

Variations across Europe in hospitalization and management of pregnant women with SARS-CoV-2 during the initial phase of the pandemic: Multi-national population-based cohort study using the International Network of Obstetric Survey Systems (INOSS).

Odette de Bruin, Hilde Engjom, Nicola Vousden, Rema Ramakrishnan, Anna J M Aabakke, Outi Äyräs, Serena Donati, Eva Jónasdóttir, Marian Knight, Evelien M Overtoom and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Adverse outcomes among pregnant women with COVID-19 according to hospitalization status: A prospective individual participant data meta-analysis in Europe and North America.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 9 countries.

Odette de BruinDepartment of Obstetrics, Birth Center Wilhelmina Children's Hospital, Division Woman and Baby, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0001-6295-3411
Hilde EngjomDivision of Mental and Physical Health, Norwegian Institute of Public Health, Bergen, Norway.ORCID 0000-0003-1582-4283
Nicola VousdenNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Rema RamakrishnanNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Anna J M AabakkeDepartment of Obstetrics and Gynecology, Copenhagen University Hospital-Holbaek, Holbaek, Denmark.ORCID 0000-0003-4754-506X
Outi ÄyräsDepartment of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0002-2423-611X
Serena DonatiNational Center for Disease Prevention and Health Promotion, Istituto Superiore di Sanità - Italian National Institute of Health, Rome, Italy.ORCID 0000-0002-4607-2072
Eva JónasdóttirDepartment of Obstetrics and Gynecology, Landspitali University Hospital, Reykjavik, Iceland.
Marian KnightNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID 0000-0002-1984-4575
Evelien M OvertoomDepartment of Obstetrics, Birth Center Wilhelmina Children's Hospital, Division Woman and Baby, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0001-6454-4531
Michele A SalvatoreNational Center for Disease Prevention and Health Promotion, Istituto Superiore di Sanità - Italian National Institute of Health, Rome, Italy.
Miriam C J M SturkenboomDepartment of Biostatistics and Research Support, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
Teresia SvanvikRegion Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg, Sweden.ORCID 0000-0003-1947-679X
Reetta VarpulaDepartment of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
An VercoutereDepartment of Obstetrics and Gynecology, CUB Hôpital Erasme, Hôpital Universitaire de Bruxelles (H.U.B.), Université Libre de Bruxelles (ULB), Brussels, Belgium.
Kitty W M BloemenkampDepartment of Obstetrics, Birth Center Wilhelmina Children's Hospital, Division Woman and Baby, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0002-1377-4625
INOSS COVID-19 Working Group
University Medical Center Utrecht · NLUniversity of Oxford · GBIstituto Superiore di Sanità · ITUniversity of Helsinki · FICopenhagen University Hospital · DKNorwegian Institute of Public Health · NOReykjavík University · ISSahlgrenska University Hospital · SEUniversité Libre de Bruxelles · BE

Funding

Belgian Federal Public Service of HealthEasyTrialEuropean Medicines Agency EMA/2018/28/PEFinska LäkaresällskapetHealth Services and Delivery Research Program 11/46/12Health Services and Delivery Research Programme 11/46/12Helsinki University Central HospitalThe Nordic Federation of Obstetrics and Gynecology 6505 2020The Region of Southern Denmark and Region Zealand A767
6 · The paper itself

Abstract

introductionThe majority of data on COVID-19 in pregnancy are not from sound population-based active surveillance systems. MATERIAL AND

methodsWe conducted a multi-national study of population-based national or regional prospective cohorts using standardized definitions within the International Network of Obstetric Survey systems (INOSS). From a source population of women giving birth between March 1 and August 31, 2020, we included pregnant women admitted to hospital with a positive SARS-CoV-2 PCR test ≤7 days prior to or during admission and up to 2 days after birth. The admissions were further categorized as COVID-19-related or non-COVID-19-related. The primary outcome of interest was incidence of COVID-19-related hospital admission. Secondary outcomes included severe maternal disease (ICU admission and mechanical ventilation) and COVID-19-directed medical treatment.

resultsIn a source population of 816 628 maternities, a total of 2338 pregnant women were admitted with SARS-CoV-2; among them 940 (40%) were COVID-19-related admissions. The pooled incidence estimate for COVID-19-related admission was 0.59 (95% confidence interval 0.27-1.02) per 1000 maternities, with notable heterogeneity across countries (I

conclusionsDuring the initial months of the pandemic, we found substantial variations in incidence of COVID-19-related admissions in nine European countries. Few pregnant women received COVID-19-directed medical treatment. Several barriers to rapid surveillance were identified. Investment in robust surveillance should be prioritized to prepare for future pandemics.

Indexed as

COVID-19Pregnancy Complications, InfectiousVenous ThromboembolismAnticoagulantsCohort StudiesEuropeFemaleHospitalizationHumansInfantPandemicsPregnancyPregnant PeopleProspective StudiesSARS-CoV-2AnticoagulantsCOVID-19hospitalizationneonateobstetric surveillance systempregnancySARS-CoV-2

Identifiers

PMID37594175
PMCPMC10577630
OpenAlexW4385968380

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.