ArticleEnvironment international2023
Prenatal air pollution, maternal immune activation, and autism spectrum disorder.
Article in Environment international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- The Association Between Maternal Asthma and Child Autism: A Systematic Review and Meta-Analysis.Autism research : official journal of the International Society for Autism Research · 2025Pooled it
- Association between maternal asthma and ASD/ADHD in offspring: A meta-analysis based on observational studies.NPJ primary care respiratory medicine · 2025Pooled it
- Exposure to heavy metals in utero and autism spectrum disorder at age 3: a meta-analysis of two longitudinal cohorts of siblings of children with autism.Environmental health : a global access science source · 2024Pooled it
- Maternal NKG2D-mediated immune activation shapes fetal neural development.Molecular psychiatry · 2026Article
- Prenatal exposure to air pollution and the development of autism spectrum disorder from birth to adolescence: A nationwide Danish cohort study.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Fine and ultrafine particulate matter components and autism spectrum disorder (ASD).Environment international · 2026Article
- Combined effects of nitrogen dioxide and ozone air pollution on maternal liver function during pregnancy: a birth cohort study in China.Environmental health and preventive medicine · 2026Article
- Refractive Errors, Amblyopia Risk, and Prenatal Factors in Children with Autism Spectrum Disorder: A Cross-Sectional Study.International journal of general medicine · 2026Article
- Prenatal Exposure to Fine Particulate Matter Components and Autism Risk in Childhood.JAMA network open · 2025Article
- Zebrafish in neurodevelopmental disorders studies: Genetic models and pathological involvement of microglia.Developmental medicine and child neurology · 2025Review
- Urban mental health: a position paper of the European psychiatric association.European psychiatry : the journal of the Association of European Psychiatrists · 2025Review
- The Interplay of Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation in Autism Spectrum Disorder: Behavioral Implications and Therapeutic Strategies.Brain sciences · 2025Review
- Non-Coding RNAs in Neurodevelopmental Disorders-From Diagnostic Biomarkers to Therapeutic Targets: A Systematic Review.Biomedicines · 2025Review
- Review
- The association between long-term PM2.5 exposure and risk for pancreatic cancer: an application of social informatics.American journal of epidemiology · 2025Article
- The protracted neurotoxic consequences in mice of developmental exposures to inhaled iron nanoparticles alone or in combination with SOFrontiers in behavioral neuroscience · 2025Article
- Maternal COVID-19 Infection during Pregnancy among Children Born between 3/2020 and 2/2023 and Potential Disparities.Journal of community medicine & public health · 2025Article
- Prenatal Poly I:C exposure affects tryptophan-kynurenine metabolism associated with intestinal microbiome in female juvenile rats.Frontiers in immunology · 2025Article
- Linking ambient air pollution to mental health: evidence based on the two-sample Mendelian randomization and colocalization study.Translational psychiatry · 2024Article
- Impact of Maternal Environment and Inflammation on Fetal Neurodevelopment.Antioxidants (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundAutism Spectrum Disorder (ASD) risk is highly heritable, with potential additional non-genetic factors, such as prenatal exposure to ambient particulate matter with aerodynamic diameter < 2.5 µm (PM
objectivesThis study examined interactions between MIA-related conditions and prenatal PM
methodsIn a population-based pregnancy cohort of children born between 2001 and 2014 in Southern California, 318,751 mother-child pairs were followed through electronic medical records (EMR); 4,559 children were diagnosed with ASD before age 5. Four broad categories of MIA-related conditions were classified, including infection, hypertension, maternal asthma, and autoimmune conditions. Average exposures to PM
resultsASD risk was associated with MIA-related conditions [infection (hazard ratio 1.11; 95% confidence interval 1.05-1.18), hypertension (1.30; 1.19-1.42), maternal asthma (1.22; 1.08-1.38), autoimmune disease (1.19; 1.09-1.30)], with higher pregnancy PM
conclusionsMIA-related conditions and pregnancy PM
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.