Evidence map›Paper›PMID 37598204›Full record

ArticleBMC psychiatry2023

Joint effects of depressive status and body mass index on the risk of incident hypertension in aging population: evidence from a nationwide population-based cohort study.

Qiuxia Luo, Kai Bao, Wenlong Gao, Yuanyuan Xiang, Ming Li, Yuqi Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qiuxia LuoDepartment of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, Gansu, P. R. China.
Kai BaoDepartment of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, Gansu, P. R. China.
Wenlong GaoDepartment of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, Gansu, P. R. China. gaowl2019@sina.com.
Yuanyuan XiangDepartment of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, Gansu, P. R. China.
Ming LiDepartment of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, Gansu, P. R. China.
Yuqi ZhangDepartment of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, Gansu, P. R. China.
Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of depressive status (DS) on hypertension incidence is still controversial and has not been studied in Chinese middle-aged and elderly population. This study aimed to explore the relationship between DS and incident hypertension and analyze the joint effects of DS and body mass index (BMI) on hypertension incidence.

methodsWe conducted a prospective cohort study using data from the China Health and Retirement Longitudinal Study (CHARLS), a nationwide population-based study. In 2013, DS was identified using scores from the 10-item Centre for Epidemiological Studies Depression Scale (CES-D-10) among eligible respondents from CHARLS, and hypertension occurrence was observed until 2018. The multiple Cox models were employed to calculate the associations between DS and hypertension incidence. In addition, we also computed the multiplicative interaction (MI) between DS and BMI of incident hypertension and assessed their additive interaction (AI) through relative excess risk due to interaction (RERI), attributable proportion (AP) or synthetic index (S). Positive AI was indicated by RERI > 0, AP > 0 or S > 1.

resultsOver the 5-year follow-up, depressive symptoms increased the risk of hypertension incidence by 19% (hazard ratio (HR) = 1.19, 95% confidence interval (CI): (1.01, 1.41)), while depression was associated with a 24% increased risk (HR = 1.24; 95% CI: (1.03, 1.50)). Significant MIs between DS and overweight or obesity were observed and almost all of AI indexes showed positive joint effects on incident hypertension, of which the depression-obesity combination had the largest joint effect (RERI = 4.47, 95%CI: (0.28, 8.66); AP = 0.67, 95%CI: (0.50, 0.85); S = 4.86,95%CI: (2.66, 8.86)).

conclusionDS could lead to hypertension and this impact was amplified when coexisting with higher BMI. It highlighted a need for precise interventions targeting weight management and depression treatment in the aging population to prevent hypertension.

Indexed as

AgingHypertensionAgedBody Mass IndexCohort StudiesHumansLongitudinal StudiesMiddle AgedObesityProspective StudiesBMI: body mass indexDepressionDepressive symptomsIncident hypertensionJoint effect

Identifiers

PMID37598204
PMCPMC10439533
OpenAlexW4386000320

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.