Evidence map›Paper›PMID 37598728›Full record

ArticleJournal of molecular biology2023

Disruption of Ebola NP

Chao Wu, Nicole D Wagner, Austin B Moyle, Annie Feng, Nitin Sharma, Sarah H Stubbs, Callie Donahue, Robert A Davey, Michael L Gross, Daisy W Leung and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. 25 Years of Ebola Virus VP35 Research.Journal of molecular biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Chao WuDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. Electronic address: wuchao@szbl.ac.cn.
Nicole D WagnerDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO, USA; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Austin B MoyleDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO, USA.
Annie FengDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Nitin SharmaDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Sarah H StubbsDepartment of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
Callie DonahueDepartment of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
Robert A DaveyDepartment of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA, USA.
Michael L GrossDepartment of Chemistry, Washington University in St. Louis, St. Louis, MO, USA.
Daisy W LeungDepartment of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. Electronic address: dwleung@wustl.edu.
Gaya K AmarasingheDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. Electronic address: gamarasinghe@wustl.edu.
Washington University in St. Louis · USBoston University · US

Funding

Virology BSL4 CoreP01AI120943 · NIAID · WASHINGTON UNIVERSITY · PI Gaya K. Amarasinghe · 2016 to 2026
$30.2M
TrainingP41GM103422 · NIGMS · WASHINGTON UNIVERSITY · PI YARASHESKI, KEVIN E · 2012 to 2019
$12.0M
Novel VP30-host Interactions that Negatively Regulate Ebola Virus InfectionR01AI143292 · NIAID · WASHINGTON UNIVERSITY · PI AMARASINGHE, GAYA K., BASLER, CHRISTOPHER F · 2019 to 2023
$4.0M
Intersection Between Viral Translation and Innate Immunity in the Context of Filovirus InfectionR01AI148663 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BASLER, CHRISTOPHER F · 2020 to 2024
$3.0M
Development and characterization of engineered therapeutic antibodies against SARS-CoV-2R01AI161374 · NIAID · WASHINGTON UNIVERSITY · PI AMARASINGHE, GAYA K. · 2021 to 2023
$2.7M
A Biomedical Mass Spectrometry Resource: Ongoing Driving Biomedical ProjectsR24GM136766 · NIGMS · WASHINGTON UNIVERSITY · PI GROSS, MICHAEL L · 2020 to 2022
$2.3M
Multi-platform High Throughput Screens for Filoviral Replication InhibitorsR01AI123926 · NIAID · WASHINGTON UNIVERSITY · PI AMARASINGHE, GAYA K. · 2016 to 2018
$2.1M
STRUCTURAL BASIS FOR IMMUNE EVASION BY RSV NON-STRUCTURAL PROTEINSR01AI107056 · NIAID · WASHINGTON UNIVERSITY · PI LEUNG, DAISY W · 2013 to 2017
$1.9M
NIAID NIH HHS P01 AI120943NIAID NIH HHS R01 AI107056NIAID NIH HHS R01 AI123926NIAID NIH HHS R01 AI143292NIAID NIH HHS R01 AI148663NIAID NIH HHS R01 AI161374NIGMS NIH HHS P41 GM103422NIGMS NIH HHS R24 GM136766
6 · The paper itself

Abstract

Viral inclusion bodies (IBs) are potential sites of viral replication and assembly. How viral IBs form remains poorly defined. Here we describe a combined biophysical and cellular approach to identify the components necessary for IB formation during Ebola virus (EBOV) infection. We find that the eNP

Indexed as

EbolavirusHemorrhagic Fever, EbolaInclusion BodiesNucleoproteinsVirus ReplicationHumansNucleocapsid ProteinsViral Regulatory and Accessory ProteinsNucleocapsid ProteinsNucleoproteinsnucleoprotein VP35, Ebola virusViral Regulatory and Accessory Proteinsbiomolecular condensateEbolainclusion bodyphase separationviral replication organelle

Identifiers

PMID37598728
PMCPMC11312838
OpenAlexW4386002467

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.