ArticleFrontiers in nutrition2023
The effects of rutin supplement on blood pressure markers, some serum antioxidant enzymes, and quality of life in patients with type 2 diabetes mellitus compared with placebo.
Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Green-Synthesized Gold Nanoparticles UsingPharmaceutics · 2026Article
- A putative SGLT-relevant mechanistic perspective on quercetin-3-O-glucoside and rutin in diabetic kidney disease.Diabetology & metabolic syndrome · 2026Review
- Determination of the Optimal Cut-Off Point of Anthropometric Indices to Predict the Risk of Metabolic Syndrome in Iranian Adult Population With Type 2 Diabetes Mellitus: A Cross-Sectional-Analytical Study.Endocrinology, diabetes & metabolism · 2026Article
- Article
- Therapeutic Effects of the Most Common Polyphenols Found inNutrients · 2026Review
- Comparative analysis of key phytochemicals and biological activities of Tartary buckwheat and Flos Sophorae Immaturus.Scientific reports · 2025Article
- The Biologically Active Compounds in Fruits of Cultivated Varieties and Wild Species of Apples.Molecules (Basel, Switzerland) · 2025Review
- Pharmacological Overview of Bioactive Natural Products fromPlants (Basel, Switzerland) · 2025Review
- Flavonol Technology: From the Compounds' Chemistry to Clinical Research.Molecules (Basel, Switzerland) · 2025Review
- Current strategies for rutin nano-formulation; a promising bioactive compound with increased efficacy.Bioprocess and biosystems engineering · 2025Review
- Research Progress on Hypoglycemic Effects and Molecular Mechanisms of Flavonoids: A Review.Antioxidants (Basel, Switzerland) · 2025Review
- Rutin: a pain-relieving flavonoid.Inflammopharmacology · 2025Review
- Protective Role of Dietary Polyphenols in the Management and Treatment of Type 2 Diabetes Mellitus.Nutrients · 2025Review
- Linking oxidative stress biomarkers to disease progression and antioxidant therapy in hypertension and diabetes mellitus.Frontiers in molecular biosciences · 2025Review
- Advanced Nanotechnological Approaches for Effective Delivery of Rutin: An Updated Review.Pharmaceutical nanotechnology · 2025Review
- Review
- Exploring Conventional and Green Extraction Methods for Enhancing the Polyphenol Yield and Antioxidant Activity ofPlants (Basel, Switzerland) · 2024Article
- Antidiabetic Potential ofMedicina (Kaunas, Lithuania) · 2024Article
- Assessing the predictive value of insulin resistance indices for metabolic syndrome risk in type 2 diabetes mellitus patients.Scientific reports · 2024Article
- Exploring Beneficial Properties of Haskap Berry Leaf Compounds for Gut Health Enhancement.Antioxidants (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This trial aimed to investigate the effects of rutin supplement in type 2 diabetes mellitus (T2DM) patients. Methods: In this trial with a double-blind and controlled design, fifty patients were randomly divided into intervention ( Results: Rutin consumption caused a significant reduction in SBP, DBP, PP, MAP, and HR, with a significant increase in SOD, CAT, and GPx and some QOL parameters (emotional limitations, energy and freshness, mental health, social performance, and general health) compared with baseline ( Conclusion: Rutin consumption improved blood pressure, the levels of antioxidant enzymes, and QOL in patients with T2DM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.