Evidence map›Paper›PMID 37601968›Full record

ArticleCell genomics2023

Vanessa Tsui, Ruqian Lyu, Stevan Novakovic, Jessica M Stringer, Jessica E M Dunleavy, Elissah Granger, Tim Semple, Anna Leichter, Luciano G Martelotto, D Jo Merriner and 10 more

Open access · goldAbstract read
In one paragraph

Article in Cell genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  3. Double jeopardy: howFrontiers in cell and developmental biology · 2026
    Review
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  8. [Homozygous Variant ofSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Vanessa TsuiDNA Repair and Recombination Laboratory, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Ruqian LyuBioinformatics and Cellular Genomics, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Stevan NovakovicDNA Repair and Recombination Laboratory, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Jessica M StringerOvarian Biology Laboratory, Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIC, Australia.
Jessica E M DunleavyMale Infertility and Germ Cell Biology Group, School of BioSciences and the Bio21 Institute, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.
Elissah GrangerDNA Repair and Recombination Laboratory, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Tim SempleSingle Cell Innovation Laboratory, Centre for Cancer Research, University of Melbourne, Parkville, VIC, Australia.
Anna LeichterSingle Cell Innovation Laboratory, Centre for Cancer Research, University of Melbourne, Parkville, VIC, Australia.
Luciano G MartelottoSingle Cell Innovation Laboratory, Centre for Cancer Research, University of Melbourne, Parkville, VIC, Australia.
D Jo MerrinerMale Infertility and Germ Cell Biology Group, School of BioSciences and the Bio21 Institute, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.
Ruijie LiuBioinformatics and Cellular Genomics, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Lucy McNeillDNA Repair and Recombination Laboratory, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Nadeen ZerafaOvarian Biology Laboratory, Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIC, Australia.
Eva R HoffmannDNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Moira K O'BryanMale Infertility and Germ Cell Biology Group, School of BioSciences and the Bio21 Institute, Faculty of Science, The University of Melbourne, Parkville, VIC, Australia.
Karla HuttOvarian Biology Laboratory, Biomedicine Discovery Institute, Department of Anatomy and Developmental Biology, Monash University, Melbourne, VIC, Australia.
Andrew J DeansThe Faculty of Medicine, Dentistry and Health Science, The University of Melbourne, Parkville, VIC, Australia.
Jörg HeierhorstThe Faculty of Medicine, Dentistry and Health Science, The University of Melbourne, Parkville, VIC, Australia.
Davis J McCarthyBioinformatics and Cellular Genomics, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Wayne CrismaniDNA Repair and Recombination Laboratory, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
The University of Melbourne · AUAustralian Regenerative Medicine Institute · AUSt Vincents Institute of Medical Research · AUUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meiotic crossovers are required for accurate chromosome segregation and producing new allelic combinations. Meiotic crossover numbers are tightly regulated within a narrow range, despite an excess of initiating DNA double-strand breaks. Here, we reveal the tumor suppressor FANCM as a meiotic anti-crossover factor in mammals. We use unique large-scale crossover analyses with both single-gamete sequencing and pedigree-based bulk-sequencing datasets to identify a genome-wide increase in crossover frequencies in

Identifiers

PMID37601968
PMCPMC10435384
OpenAlexW4382722612

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.