Evidence map›Paper›PMID 37608124›Full record

Trial reportEuropean journal of applied physiology2024

Caffeine intake enhances peak oxygen uptake and performance during high-intensity cycling exercise in moderate hypoxia.

Tze-Huan Lei, Qiyang Qin, Olivier Girard, Toby Mündel, Ran Wang, Li Guo, Yinhang Cao

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tze-Huan LeiCollege of Physical Education, Hubei Normal University, Huangshi, China.ORCID http://orcid.org/0000-0003-3157-099X
Qiyang QinSchool of Athletic Performance, Shanghai University of Sport, Shanghai, 200438, China.ORCID http://orcid.org/0000-0001-8890-7261
Olivier GirardSchool of Human Sciences (Exercise and Sport Science), The University of Western Australia, Perth, Australia.ORCID http://orcid.org/0000-0002-4797-182X
Toby MündelDepartment of Kinesiology, Brock University, St. Catharines, Canada.ORCID http://orcid.org/0000-0002-4214-8543
Ran WangSchool of Athletic Performance, Shanghai University of Sport, Shanghai, 200438, China.ORCID http://orcid.org/0000-0002-7148-0764
Li GuoSchool of Exercise and Health, Shanghai University of Sport, Shanghai, China.ORCID http://orcid.org/0009-0007-1206-3614
Yinhang CaoSchool of Athletic Performance, Shanghai University of Sport, Shanghai, 200438, China. caoyinhang@sus.edu.cn.ORCID http://orcid.org/0000-0003-2323-3707

Funding

research project of Shanghai University of Sport 2022XJ020Shanghai Key Lab of Human Performance at Shanghai University of Sport 11DZ2261100
6 · The paper itself

Abstract

purposeWe investigated whether caffeine consumption can enhance peak oxygen uptake ([Formula: see text]) by increasing peak ventilation during an incremental cycling test, and subsequently enhance time to exhaustion (TTE) during high-intensity cycling exercise in moderate normobaric hypoxia.

methodsWe conducted a double-blind, placebo cross-over design study. Sixteen recreational male endurance athletes (age: 20 ± 2 years, [Formula: see text]: 55.6 ± 3.6 ml/kg/min, peak power output: 318 ± 40 W) underwent an incremental cycling test and a TTE test at 80% [Formula: see text] (derived from the placebo trial) in moderate normobaric hypoxia (fraction of inspired O

resultsCaffeine consumption resulted in a higher peak ventilation [159 ± 21 vs. 150 ± 26 L/min; P < 0.05; effect size (ES) = 0.31]. [Formula: see text] (3.58 ± 0.44 vs. 3.47 ± 0.47 L/min; P < 0.01; ES = 0.44) and peak power output (308 ± 44 vs. 302 ± 44 W; P = 0.02, ES = 0.14) were higher following caffeine consumption than during the placebo trial. During the TTE test, caffeine consumption enhanced minute ventilation (P = 0.02; ES = 0.28) and extended the TTE (426 ± 74 vs. 358 ± 75 s; P < 0.01, ES = 0.91) compared to the placebo trial. There was a positive correlation between the percent increase of [Formula: see text] following caffeine consumption and the percent increase in TTE (r = 0.49, P < 0.05).

conclusionModerate caffeine consumption stimulates breathing and aerobic metabolism, resulting in improved performance during incremental and high-intensity endurance exercises in moderate normobaric hypoxia.

Indexed as

CaffeinePhysical EnduranceAdolescentAdultExerciseExercise TestHumansHypoxiaMaleOxygenOxygen ConsumptionYoung AdultCaffeineOxygenErgogenic aidExercise capacityExhaustionHypoxia exposureIncremental exerciseVentilation

Identifiers

PMID37608124

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.