Evidence map›Paper›PMID 37608935›Full record

ArticleArXiv2023

Simultaneous tensile and shear measurement of the human cornea

Guo-Yang Li, Xu Feng, Seok-Hyun Yun

Open access · greenAbstract readPreprint
PubMed Full text at PMC
In one paragraph

Article in ArXiv, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 18 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Guo-Yang LiHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.
Xu FengHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.
Seok-Hyun YunHarvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114, USA.
Harvard University · US

Funding

In vivo high-resolution mapping of the elastic moduli and tensile stress in the human corneaR01EY034857 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI Seok-Hyun Andy Yun · 2023 to 2026
$2.1M
In vivo optical coherence elastography of the cornea: mapping shear and tensile moduliR01EY033356 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI YUN, SEOK-HYUN ANDY · 2022 to 2024
$1.2M
NEI NIH HHS R01 EY033356NEI NIH HHS R01 EY034857
6 · The paper itself

Abstract

Understanding corneal stiffness is valuable for improving refractive surgery, detecting corneal abnormalities, and assessing intraocular pressure. However, accurately measuring the elastic properties, particularly the tensile and shear moduli that govern mechanical deformation, has been challenging. To tackle this issue, we have developed guided-wave optical coherence elastography that can simultaneously excite and analyze symmetric (S0) and anti-symmetric (A0) elastic waves in the cornea at frequencies around 10 kHz and allows us to extract tensile and shear properties from measured wave dispersion curves. By applying acoustoelastic theory that incorporates corneal tension and a nonlinear constitutive tissue model, we verified the technique using elastomer phantoms and

Indexed as

Corneaguided wavein vivomechanical anisotropyoptical coherence elastography

Identifiers

PMID37608935
PMCPMC10441437
OpenAlexW4385774789

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.