Evidence map›Paper›PMID 37612299›Full record

ArticleNature communications2023

Hypothermal opto-thermophoretic tweezers.

Pavana Siddhartha Kollipara, Xiuying Li, Jingang Li, Zhihan Chen, Hongru Ding, Youngsun Kim, Suichu Huang, Zhenpeng Qin, Yuebing Zheng

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Ice-phase optothermal tweezers.Nature communications · 2026
    Article
  3. A nanoscale robotic cleaner.Nature communications · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Ludwig-Soret microscopy with the vibrational photothermal effect.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Perspective: Thermophoresis and Its Promise for Optical Patterning.Langmuir : the ACS journal of surfaces and colloids · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Thermo-optical tweezers based on photothermal waveguides.Microsystems & nanoengineering · 2024
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Pavana Siddhartha KolliparaWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX, 78712, USA.ORCID http://orcid.org/0000-0003-0166-6720
Xiuying LiDepartment of Mechanical Engineering, The University of Texas at Dallas, Richardson, TX, 75080, USA.
Jingang LiMaterials Science and Engineering Program and Texas Materials Institute, The University of Texas at Austin, Austin, TX, 78712, USA.
Zhihan ChenMaterials Science and Engineering Program and Texas Materials Institute, The University of Texas at Austin, Austin, TX, 78712, USA.
Hongru DingWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX, 78712, USA.ORCID http://orcid.org/0000-0003-1579-6825
Youngsun KimMaterials Science and Engineering Program and Texas Materials Institute, The University of Texas at Austin, Austin, TX, 78712, USA.ORCID http://orcid.org/0000-0001-5219-8408
Suichu HuangKey Laboratory of Micro-Systems and Micro-Structures Manufacturing of Ministry of Education and School of Mechatronics Engineering, Harbin Institute of Technology, Harbin, 15001, China.
Zhenpeng QinDepartment of Mechanical Engineering, The University of Texas at Dallas, Richardson, TX, 75080, USA.ORCID http://orcid.org/0000-0003-3406-3045
Yuebing ZhengWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX, 78712, USA. zheng@austin.utexas.edu.ORCID http://orcid.org/0000-0002-9168-9477

Funding

Development of new photo-releasable neuropeptide nano-vesicles for studying modulation in the brainRF1NS110499 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI QIN, ZHENPENG, SLESINGER, PAUL A · 2019 to 2019
$2.4M
Optical Control of Protein Activity in Live Cells by Plasmon Assisted Light InactivationR35GM133653 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI QIN, ZHENPENG · 2019 to 2023
$2.2M
Four-dimensional Adhesion Frequency Assay for Full Profiling of Receptor-ligand Interactions on CellsR01GM146962 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ZHENG, YUEBING · 2022 to 2025
$1.5M
NIGMS NIH HHS R01 GM146962NIGMS NIH HHS R35 GM133653NINDS NIH HHS RF1 NS110499
6 · The paper itself

Abstract

Optical tweezers have profound importance across fields ranging from manufacturing to biotechnology. However, the requirement of refractive index contrast and high laser power results in potential photon and thermal damage to the trapped objects, such as nanoparticles and biological cells. Optothermal tweezers have been developed to trap particles and biological cells via opto-thermophoresis with much lower laser powers. However, the intense laser heating and stringent requirement of the solution environment prevent their use for general biological applications. Here, we propose hypothermal opto-thermophoretic tweezers (HOTTs) to achieve low-power trapping of diverse colloids and biological cells in their native fluids. HOTTs exploit an environmental cooling strategy to simultaneously enhance the thermophoretic trapping force at sub-ambient temperatures and suppress the thermal damage to target objects. We further apply HOTTs to demonstrate the three-dimensional manipulation of functional plasmonic vesicles for controlled cargo delivery. With their noninvasiveness and versatile capabilities, HOTTs present a promising tool for fundamental studies and practical applications in materials science and biotechnology.

Indexed as

BiotechnologyCD40 LigandCold TemperatureCommerceHot TemperatureCD40 Ligand

Identifiers

PMID37612299
PMCPMC10447564

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.