Evidence map›Paper›PMID 37614820›Full record

ArticleFrontiers in genetics2023

Case report: Progressive pulmonary artery hypertension in a case of megalencephaly-capillary malformation syndrome.

Yuri Yoh, Tadashi Shiohama, Tomoko Uchida, Ryota Ebata, Hironobu Kobayashi, Kentaro Okunushi, Mitsuhiro Kato, Kazuki Watanabe, Mitsuko Nakashima, Hirotomo Saitsu and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yuri YohDepartment of Pediatrics, Chiba University Hospital, Chiba, Japan.
Tadashi ShiohamaDepartment of Pediatrics, Chiba University Hospital, Chiba, Japan.
Tomoko UchidaDepartment of Pediatrics, Chiba University Hospital, Chiba, Japan.
Ryota EbataDepartment of Pediatrics, Chiba University Hospital, Chiba, Japan.
Hironobu KobayashiDepartment of Pediatrics, Chiba University Hospital, Chiba, Japan.
Kentaro OkunushiDepartment of Pediatrics, Chiba University Hospital, Chiba, Japan.
Mitsuhiro KatoDepartment of Pediatrics, Showa University School of Medicine, Tokyo, Japan.
Kazuki WatanabeDepartment of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Mitsuko NakashimaDepartment of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Hirotomo SaitsuDepartment of Biochemistry, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Hiromichi HamadaDepartment of Pediatrics, Chiba University Hospital, Chiba, Japan.
Chiba University Hospital · JPHamamatsu University School of Medicine · JPShowa University · JP

Funding

Wellcome Trust FC001039
6 · The paper itself

Abstract

Megalencephaly-capillary malformation syndrome (MCAP, OMIM # 602501) is caused by hyperactivity of the thephosphoinositide-3-kinase (PI3K)-Vakt murine thymoma viral oncogene homolog (AKT)-mammalian target of rapamycin (mTOR) pathway, which results in megalencephaly, capillary malformations, asymmetrical overgrowth, and connective tissue dysplasia. Herein, we report the case of a 7-month-old girl with MCAP due to a

Indexed as

megalencephaly-capillary malformation syndromeovergrowth syndromePI3K/Akt/mTOR pathwayPIK3CApulmonary arterial hypertension

Identifiers

PMID37614820
PMCPMC10442816
OpenAlexW4385664237

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.