Evidence map›Paper›PMID 37619289›Full record

ReviewCurrent opinion in cell biology2023

Intermediate, but not average: The unusual lives of the nuclear lamin proteins.

Abigail Buchwalter

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Synthesis of Benzo[JACS Au · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Exceptionally long-lived nuclear RNAs.Science (New York, N.Y.) · 2024
    Article
  11. Review
  12. Review
  13. Lamins as structural nuclear elements through evolution.Current opinion in cell biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Abigail BuchwalterCardiovascular Research Institute and Department of Physiology, University of California, San Francisco, San Francisco, CA, USA; Chan Zuckerberg Biohub, San Francisco, CA, USA. Electronic address: abigail.buchwalter@ucsf.edu.

Funding

Understanding mechanisms of heterochromatin tethering at the nuclear laminaR35GM142897 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Abigail Lynn Buchwalter · 2021 to 2026
$2.4M
Exploring modulation of Lamin A/C protein lifetime as a novel axis of regulation in heath and diseaseR01AR084208 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Abigail Lynn Buchwalter · 2024 to 2026
$1.3M
NIAMS NIH HHS R01 AR084208NIGMS NIH HHS R35 GM142897
6 · The paper itself

Abstract

The nuclear lamins are polymeric intermediate filament proteins that scaffold the nucleus and organize the genome in nearly all eukaryotic cells. This review focuses on the dynamic regulation of lamin filaments through their biogenesis, assembly, disassembly, and degradation. The lamins are unusually long-lived proteins under homeostatic conditions, but their turnover can be induced in select contexts that are highlighted in this review. Finally, we discuss recent investigations into the influence of laminopathy-linked mutations on the assembly, folding, and stability of the nuclear lamins.

Indexed as

Intermediate FilamentsNuclear LaminaCell NucleusEukaryotic CellsLaminsLamins

Identifiers

PMID37619289
PMCPMC12049094

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.