Evidence map›Paper›PMID 37620160›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Cleavage of VAMP2/3 Affects Oligodendrocyte Lineage Development in the Developing Mouse Spinal Cord.

Christopher D Fekete, Robert Z Horning, Matan S Doron, Akiko Nishiyama

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Vesicle Fusion in Oligodendrocyte Maturation and Myelination.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christopher D FeketeDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269.
Robert Z HorningDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269.
Matan S DoronDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269.
Akiko NishiyamaDepartment of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut 06269 akiko.nishiyama@uconn.edu.ORCID 0000-0001-7252-0812
University of Connecticut · US

Funding

Inflammation and NG2 Cell DifferentiationR01NS073425 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2011 to 2021
$3.3M
SNARE complex-mediated exocytosis in oligodendrocyte differentiation and survivalR01NS116182 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2020 to 2024
$1.7M
Heterogeneity of NG2 Glial CellsR01NS074870 · NINDS · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2012 to 2016
$1.7M
Leica TCS SP8 FSU AOBS 405 UV Spectral Confocal MicroscopeS10OD016435 · OD · UNIVERSITY OF CONNECTICUT STORRS · PI NISHIYAMA, AKIKO · 2014 to 2014
$456k
NIH HHS S10 OD016435NINDS NIH HHS R01 NS073425NINDS NIH HHS R01 NS074870NINDS NIH HHS R01 NS116182
6 · The paper itself

Abstract

In the developing and adult CNS, new oligodendrocytes (OLs) are generated from a population of cells known as oligodendrocyte precursor cells (OPCs). As they begin to differentiate, OPCs undergo a series of highly regulated changes to morphology, gene expression, and membrane organization. This stage represents a critical bottleneck in oligodendrogliogenesis, and the regulatory program that guides it is still not fully understood. Here, we show that

Indexed as

Vesicle-Associated Membrane Protein 2White MatterAnimalsCell DifferentiationCell LineageFemaleMaleMiceMice, TransgenicMyelin SheathOligodendrogliaSpinal CordVesicle-Associated Membrane Protein 2Fynmyelinoligodendrocyte precursorSNAREspinal cordVAMP

Identifiers

PMID37620160
PMCPMC10538588
OpenAlexW4386127437

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.