Evidence map›Paper›PMID 37620584›Full record

ArticleNature aging2023

Medin amyloid may drive arterial aging and disease in the periphery and brain.

Jillian Madine, Hannah A Davies, Raymond Q Migrino, Sanni E Ruotsalainen, Jessica Wagner, Jonas J Neher

Abstract read
PubMed Publisher
In one paragraph

Article in Nature aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Jillian MadineInstitute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Hannah A DaviesInstitute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Raymond Q MigrinoPhoenix Veterans Affairs Health Care System and University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
Sanni E RuotsalainenInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
Jessica WagnerGerman Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
Jonas J NeherGerman Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. jonas.neher@dzne.de.ORCID http://orcid.org/0000-0003-1346-8924
German Center for Neurodegenerative Diseases · DEUniversity of Liverpool · GBUniversity of Arizona · USUniversity of Helsinki · FI

Funding

Understanding vascular aging-related dementia through medin signalingR56AG083570 · NIA · ARIZONA VETERANS RESEARCH AND EDUCATION FOUNDATION · PI LI, MING, MIGRINO, RAYMOND QUEZON · 2023 to 2023
$472k
Discovering the Origin of Vascular Aging Amyloid Protein MedinR21AG075543 · NIA · ARIZONA VETERANS RESEARCH AND EDUCATION FOUNDATION · PI LI, MING, MIGRINO, RAYMOND QUEZON · 2022 to 2022
$347k
Discovering novel mechanisms for aging-related dementia: probing medin and abeta vasculopathyI01BX003767 · VA · PHOENIX VA HEALTH CARE SYSTEM · PI MIGRINO, RAYMOND QUEZON · 2017 to 2024
–
BLRD VA I01 BX003767NIA NIH HHS R56 AG083570
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyloidogenic ProteinsBrainArteriesHeadAmyloidogenic Proteins

Identifiers

PMID37620584
OpenAlexW4386142320

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.